Nanomedicine for the effective and safe delivery of non-steroidal anti-inflammatory drugs: A review of preclinical research
The toxicity of nonsteroidal anti-inflammatory drugs (NSAIDs) is one of the major limitations
to their long-term use in the treatment of chronic inflammatory conditions. This review …
to their long-term use in the treatment of chronic inflammatory conditions. This review …
A hyaluronic acid functionalized self-nano-emulsifying drug delivery system (SNEDDS) for enhancement in ciprofloxacin targeted delivery against intracellular …
Ciprofloxacin (CIP), a potent anti-bacterial agent of the fluroquinolone family, shows poor
solubility and permeability, thus leading to the development of intracellular pathogens …
solubility and permeability, thus leading to the development of intracellular pathogens …
[HTML][HTML] Attenuation of celecoxib cardiac toxicity using Poly (δ-decalactone) based nanoemulsion via oral route
Celecoxib (CLX), a poorly soluble anti-inflammatory drug, requires administration in higher
concentrations to produce therapeutic effects, oftentimes resulting in cardiac toxicity …
concentrations to produce therapeutic effects, oftentimes resulting in cardiac toxicity …
Improving the efficacy of Cyclooxegenase-2 inhibitors in the management of oral cancer: Insights into the implementation of nanotechnology and mucoadhesion
AA Mabrouk, MI Tadros, WM El-Refaie - Journal of Drug Delivery Science …, 2021 - Elsevier
Oral carcinoma is a worldwide health threat with high rate of recurrence and metastasis.
Cyclooxygenase-2 (COX-2) enzyme is over expressed in oral cancer cells and affects …
Cyclooxygenase-2 (COX-2) enzyme is over expressed in oral cancer cells and affects …
Oral gel loaded with penciclovir–lavender oil nanoemulsion to enhance bioavailability and alleviate pain associated with herpes labialis
Herpes labialis, caused by herpes simplex virus type 1, is usually characterized by painful
skin or mucosal lesions. Penciclovir (PV) tablets are found to be effective against herpes …
skin or mucosal lesions. Penciclovir (PV) tablets are found to be effective against herpes …
Mechanistic studies on the absorption enhancement of a self-nanoemulsifying drug delivery system loaded with norisoboldine-phospholipid complex
J Zhang, X Wen, Y Dai, Y Xia - International journal of …, 2019 - Taylor & Francis
Background Norisoboldine (NOR), the main isoquinoline alkaloid constituent in Radix
Linderae, was demonstrated to have an outstanding anti-arthritis activity. However, a poor …
Linderae, was demonstrated to have an outstanding anti-arthritis activity. However, a poor …
Comparison of two self-nanoemulsifying drug delivery systems using different solidification techniques for enhanced solubility and oral bioavailability of poorly water …
MR Woo, S Woo, YW Bak, S Cheon, JS Kim… - Colloids and Surfaces B …, 2024 - Elsevier
In this study, we aimed to develop a solid self-nanoemulsifying drug delivery system (S-
SNEDDS) and a solid self-nanoemulsifying granule system (S-SNEGS) to enhance the …
SNEDDS) and a solid self-nanoemulsifying granule system (S-SNEGS) to enhance the …
A customized screening tool approach for the development of a self-nanoemulsifying drug delivery system (SNEDDS)
FP Schmied, A Bernhardt, A Engel, S Klein - AAPS PharmSciTech, 2021 - Springer
The present study focused on establishing a novel,(pre-) screening approach that enables
the development of promising performing self-nanoemulsifying drug delivery systems …
the development of promising performing self-nanoemulsifying drug delivery systems …
Buccal mucosal accumulation of dapoxetine using supersaturation, co-solvent and permeation enhancing polymer strategy
Purpose we have presented the potential of using mixed solvents, supersaturation and
penetration enhancing polymers for achieving a good route for poorly soluble and …
penetration enhancing polymers for achieving a good route for poorly soluble and …
Spray-dried self-nanoemulsifying drug delivery systems as carriers for the oral delivery of piperine: Characterization and in vitro evaluation
Piperine is the primary alkaloid compound of white pepper, which has many therapeutic
benefits. However, piperine has limitations, including low bioavailability, being …
benefits. However, piperine has limitations, including low bioavailability, being …