The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

The human stress response has evolved to maintain homeostasis under conditions of real or
perceived stress. This objective is achieved through autoregulatory neural and hormonal …

Objective To conduct a systematic review and meta‐analysis of studies that measured
cytokine and chemokine levels in individuals with major depressive disorder (MDD) …

Statins are commonly prescribed medications widely investigated for their potential actions
on the brain and mental health. Pre-clinical and clinical evidence suggests that statins may …

Animal studies and a handful of prospective human studies have demonstrated that young
offspring exposed to maternal prenatal stress show abnormalities in immune parameters …

Depressive symptoms are reported by more than 20% of people with inflammatory bowel
disease (IBD), while sleep difficulties and fatigue are even more common. Co-morbid …

Major depressive disorder has been linked to alterations in several interacting systems,
particularly with respect to neuroendocrine and neuroinflammatory dysfunction. Increased …

Sarcopenia, characterized by reduced muscle function as well as muscle mass, has been a
public health problem with increasing prevalence. It might result from aging, injury, hormone …

The cortisol awakening response (CAR), defined as the increase in cortisol release in
response to waking up, shows associations with social and environmental risk factors of …

Glucocorticoids have been suggested to be involved in several neuropsychiatric disorders,
including depression. One of the possible mechanisms through which glucocorticoids …