The maternal-to-zygotic transition revisited
The development of animal embryos is initially directed by maternal gene products. Then,
during the maternal-to-zygotic transition (MZT), developmental control is handed to the …
during the maternal-to-zygotic transition (MZT), developmental control is handed to the …
3 minutes to precisely measure morphogen concentration
T Lucas, H Tran, CA Perez Romero, A Guillou… - PLoS …, 2018 - journals.plos.org
Morphogen gradients provide concentration-dependent positional information along polarity
axes. Although the dynamics of the establishment of these gradients is well described …
axes. Although the dynamics of the establishment of these gradients is well described …
Synthetic reconstruction of the hunchback promoter specifies the role of Bicoid, Zelda and Hunchback in the dynamics of its transcription
For over 40 years, the Bicoid-hunchback (Bcd-hb) system in the fruit fly embryo has been
used as a model to study how positional information in morphogen concentration gradients …
used as a model to study how positional information in morphogen concentration gradients …
Both the transcriptional activator, Bcd, and repressor, Cic, form small mobile oligomeric clusters
L Zhang, L Hodgins, S Sakib, A Verbeem… - Biophysical …, 2024 - cell.com
Transcription factors play an essential role in pattern formation during early embryo
development, generating a strikingly fast and precise transcriptional response that results in …
development, generating a strikingly fast and precise transcriptional response that results in …
[图书][B] Single-stranded RNA phages: From molecular biology to nanotechnology
P Pumpens - 2020 - taylorfrancis.com
This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first
discovered in 1961. These phages played a unique role in early studies of molecular …
discovered in 1961. These phages played a unique role in early studies of molecular …
Using FCS to accurately measure protein concentration in the presence of noise and photobleaching
L Zhang, C Perez-Romero, N Dostatni, C Fradin - Biophysical Journal, 2021 - cell.com
Quantitative cell biology requires precise and accurate concentration measurements,
resolved both in space and time. Fluorescence correlation spectroscopy (FCS) has been …
resolved both in space and time. Fluorescence correlation spectroscopy (FCS) has been …
Synthetic deconstruction of hunchback regulation by Bicoid
G Fernandes, H Tran, M Andrieu, Y Diaw… - bioRxiv, 2021 - biorxiv.org
During development, cell identity is established reproducibly among individuals through the
expression of specific genes at the correct time and correct location in space. How genes …
expression of specific genes at the correct time and correct location in space. How genes …