Cell models and their application for studying adipogenic differentiation in relation to obesity: a review

FJ Ruiz-Ojeda, AI Rupérez, C Gomez-Llorente… - International journal of …, 2016 - mdpi.com
Over the last several years, the increasing prevalence of obesity has favored an intense
study of adipose tissue biology and the precise mechanisms involved in adipocyte …

MicroRNAs as regulators of metabolic disease: pathophysiologic significance and emerging role as biomarkers and therapeutics

JA Deiuliis - International journal of obesity, 2016 - nature.com
The prevalence of overweight and obesity in developed and developing countries has
greatly increased the risk of insulin resistance and type 2 diabetes mellitus. It is evident from …

Role of microRNAs in obesity and obesity-related diseases

G Iacomino, A Siani - Genes & nutrition, 2017 - Springer
In recent years, the link between regulatory microRNAs (miRNAs) and diseases has been
the object of intensive research. miRNAs have emerged as key mediators of metabolic …

Noncoding RNAs, cytokines, and inflammation‐related diseases

JL Marques‐Rocha, M Samblas, FI Milagro… - The FASEB …, 2015 - Wiley Online Library
Chronic inflammation is involved in the onset and development of many diseases, including
obesity, atherosclerosis, type 2 diabetes, osteoarthritis, autoimmune and degenerative …

PPARγ and Wnt signaling in adipogenic and osteogenic differentiation of mesenchymal stem cells

Z Yuan, Q Li, S Luo, Z Liu, D Luo… - Current stem cell …, 2016 - ingentaconnect.com
Mesenchymal stem cells (MSCs) arise from a variety of tissues, including bone marrow and
adipose tissue and, accordingly, have the potential to differentiate into multiple cell types …

Regulatory microRNAs in brown, brite and white adipose tissue

S Gharanei, K Shabir, JE Brown, MO Weickert… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) constitute a class of short noncoding RNAs which regulate gene
expression by targeting messenger RNA, inducing translational repression and messenger …

MicroRNA: dynamic regulators of macrophage polarization and plasticity

JB Self-Fordham, AR Naqvi, JR Uttamani… - Frontiers in …, 2017 - frontiersin.org
The ability of a healthy immune system to clear the plethora of antigens it encounters
incessantly relies on the enormous plasticity displayed by the comprising cell types …

An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications

Z Ghesmati, M Rashid, S Fayezi, F Gieseler… - Reviews in Endocrine …, 2024 - Springer
Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and
beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT …

Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells

JM Yao, HZ Ying, HH Zhang, FS Qiu, JQ Wu… - Free Radical Biology and …, 2023 - Elsevier
Exosomes containing various biological cargoes have potential to be novel diagnostic
biomarkers for metabolic diseases. In this study, retinol-binding protein 4 (RBP4) was found …

Circular RNA profiling identifies novel circPPARA that promotes intramuscular fat deposition in pigs

B Li, Y He, W Wu, X Tan, Z Wang… - Journal of Agricultural …, 2022 - ACS Publications
Intramuscular fat (IMF) content plays an important role in pork quality. Circular RNAs
(circRNAs) implicate various biological processes; however, the regulatory mechanisms and …