Biopolymer and synthetic polymer-based nanocomposites in wound dressing applications: a review

R Gobi, P Ravichandiran, RS Babu, DJ Yoo - Polymers, 2021 - mdpi.com
Biopolymers are materials obtained from a natural origin, such as plants, animals,
microorganisms, or other living beings; they are flexible, elastic, or fibrous materials …

Natural products in cosmetics

JK Liu - Natural products and bioprospecting, 2022 - Springer
The global cosmetics market reached US 500billionin2017andisexpectedtoexceedUS 800
billion by 2023, at around a 7% annual growth rate. The cosmetics industry is emerging as …

US FDA-approved therapeutic antibodies with high-concentration formulation: summaries and perspectives

SS Wang, Y Yan, K Ho - Antibody therapeutics, 2021 - academic.oup.com
Thirty four (34) of the total US FDA approved 103 therapeutic antibody drugs, accounts for
one third of the total approved mAbs, are formulated with high protein concentration (100 …

Insights into the source, mechanism and biotechnological applications of hyaluronidases

YS Zhang, JS Gong, ZY Yao, JY Jiang, C Su, H Li… - Biotechnology …, 2022 - Elsevier
It has long been found that hyaluronidases exist in a variety of organisms, playing their roles
in various biological processes including infection, envenomation and metabolic regulation …

3D printed scaffolds based on hyaluronic acid bioinks for tissue engineering: a review

H Chen, H Xue, H Zeng, M Dai, C Tang, L Liu - Biomaterials Research, 2023 - Springer
Hyaluronic acid (HA) is widely distributed in human connective tissue, and its unique
biological and physicochemical properties and ability to facilitate biological structure repair …

Paving the way towards effective plant-based inhibitors of hyaluronidase and tyrosinase: A critical review on a structure–activity relationship

J Gębalski, F Graczyk, D Załuski - Journal of Enzyme Inhibition and …, 2022 - Taylor & Francis
Human has used plants to treat many civilisation diseases for thousands of years. Examples
include reserpine (hypertension therapy), digoxin (myocardial diseases), vinblastine and …

Intratumoral electroporation of a self-amplifying RNA expressing IL-12 induces antitumor effects in mouse models of cancer

N Silva-Pilipich, A Lasarte-Cía, T Lozano… - … Therapy-Nucleic Acids, 2022 - cell.com
Alphavirus vectors based on self-amplifying RNA (saRNA) generate high and transient
levels of transgene expression and induce innate immune responses, making them an …

Hyaluronic acid-based hydrogels: As an exosome delivery system in bone regeneration

H Deng, J Wang, R An - Frontiers in Pharmacology, 2023 - frontiersin.org
Exosomes are extracellular vesicles (EVs) containing various ingredients such as DNA,
RNA, lipids and proteins, which play a significant role in intercellular communication …

Mucus-permeable polymyxin B-hyaluronic acid/poly (lactic-co-glycolic acid) nanoparticle platform for the nebulized treatment of lung infections

J Wu, T Zhai, J Sun, Q Yu, Y Feng, R Li, H Wang… - Journal of Colloid and …, 2022 - Elsevier
The aim of this study was to improve the bioavailability of polymyxin B (PMB) in pulmonary
nebulized drug delivery. To this end, we developed a nano-delivery system that penetrates …

Human hyaluronidase PH20 potentiates the antitumor activities of mesothelin-specific CAR-T cells against gastric cancer

R Zhao, Y Cui, Y Zheng, S Li, J Lv, Q Wu… - Frontiers in …, 2021 - frontiersin.org
T cell infiltration into tumors is essential for successful immunotherapy against solid tumors.
Herein, we found that the expression of hyaluronic acid synthases (HAS) was negatively …