Pathogenic role of exosomes and microRNAs in HPV‐mediated inflammation and cervical cancer: a review

J Sadri Nahand, M Moghoofei… - … journal of cancer, 2020 - Wiley Online Library
Cervical cancer (CC) is the fourth most common cause of cancer death in women. The most
important risk factor for the development of CC is cervical infection with human papilloma …

Inflammation and cancer: how hot is the link?

BB Aggarwal, S Shishodia, SK Sandur… - Biochemical …, 2006 - Elsevier
Although inflammation has long been known as a localized protective reaction of tissue to
irritation, injury, or infection, characterized by pain, redness, swelling, and sometimes loss of …

Amphiregulin

C Berasain, MA Avila - Seminars in cell & developmental biology, 2014 - Elsevier
Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely
expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored …

The multiple roles of amphiregulin in human cancer

B Busser, L Sancey, E Brambilla, JL Coll… - Biochimica et Biophysica …, 2011 - Elsevier
Amphiregulin (AREG) is one of the ligands of the epidermal growth factor receptor (EGFR).
AREG plays a central role in mammary gland development and branching morphogenesis …

Kupffer cell-derived Tnf triggers cholangiocellular tumorigenesis through JNK due to chronic mitochondrial dysfunction and ROS

D Yuan, S Huang, E Berger, L Liu, N Gross… - Cancer cell, 2017 - cell.com
Intrahepatic cholangiocarcinoma (ICC) is a highly malignant, heterogeneous cancer with
poor treatment options. We found that mitochondrial dysfunction and oxidative stress trigger …

Cell-mediated immune response to human papillomavirus infection

M Scott, M Nakagawa, AB Moscicki - Clinical Diagnostic …, 2001 - Am Soc Microbiol
Acquisition of human papillomavirus (HPV) results in an infection of variable duration which
may or may not be associated with clinically apparent lesions. Lesions caused by skintropic …

The role of inflammation in HPV carcinogenesis

E Boccardo, AP Lepique, LL Villa - Carcinogenesis, 2010 - academic.oup.com
The role of inflammation in human papillomavirus (HPV) infection and disease is complex
since it involves responses capable of preventing initial infections, clearing those ongoing …

Human papillomavirus-associated tumors of the skin and mucosa

S Majewski, S Jablonska - Journal of the American Academy of …, 1997 - Elsevier
This review discusses diseases of the lower genital tract in which the presence of human
papillomavirus (HPV) DNA is well documented. We discuss epidemiologic, clinical, and …

IL (interleukin)-1α promotes nuclear factor-κB and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas

JS Wolf, Z Chen, G Dong, JB Sunwoo, CC Bancroft… - Clinical Cancer …, 2001 - AACR
Abstract Interleukin 1α (IL-1α) is an important regulatory cytokine, the release of which after
an injury can induce activation of transcription factors nuclear factor (NF) κB and activator …

The potential contributions of chronic inflammation to lung carcinogenesis

S Ballaz, JL Mulshine - Clinical lung cancer, 2003 - Elsevier
A number of lines of evidence suggests that chronic inflammation contributes to the process
of carcinogenesis. In this article, this theme is explored with particular emphasis on the …