Reversal and preventive pleiotropic mechanisms involved in the antipsychotic-like effect of taurine, an essential β-amino acid in ketamine-induced experimental …
Schizophrenia is a life disabling, multisystem neuropsychiatric disease mostly derived from
complex epigenetic-mediated neurobiological changes causing behavioural deficits …
complex epigenetic-mediated neurobiological changes causing behavioural deficits …
Mechanisms underpinning Carpolobia lutea G. Don ethanol extract's neurorestorative and antipsychotic-like activities in an NMDA receptor antagonist model of …
Ethnopharmacological relevance Persistent ketamine insults to the central nervous system
block NMDA receptors and disrupt putative neurotransmission, oxido–nitrosative, and …
block NMDA receptors and disrupt putative neurotransmission, oxido–nitrosative, and …
Influence of the dose of ketamine used on schizophrenia-like symptoms in mice: A correlation study with TH, GAD67, and PPAR-γ
T Rodrigues, GN Bressan, BN Krum… - Pharmacology …, 2023 - Elsevier
Schizophrenia is a chronic, debilitating mental illness that has not yet been completely
understood. In this study, we aimed to investigate the effects of different doses of ketamine, a …
understood. In this study, we aimed to investigate the effects of different doses of ketamine, a …
[HTML][HTML] NMDA receptor modulation by Esculetin: Investigating behavioral, biochemical and neurochemical effects in schizophrenic mice model
I Khalid, U Saleem, B Ahmad, MF Hawwal… - Saudi Pharmaceutical …, 2024 - Elsevier
Schizophrenia, a global mental health disorder affecting approximately 1% of the
population, is characterized by neurotransmitter dysregulation, particularly dopamine …
population, is characterized by neurotransmitter dysregulation, particularly dopamine …
Nano-hesperetin attenuates ketamine-induced schizophrenia-like symptoms in mice: participation of antioxidant parameters
Rationale Antioxidant natural herb hesperetin (Hst) offers powerful medicinal properties.
Despite having noticeable antioxidant properties, it has limited absorption, which is a major …
Despite having noticeable antioxidant properties, it has limited absorption, which is a major …
Dissecting the antidepressant effect of troxerutin: modulation of neuroinflammatory and oxidative stress biomarkers in lipopolysaccharide-treated mice
The role of neuroinflammation in the pathogenesis of depression has prompted the search
for new antidepressants. Troxerutin, a bioflavonoid with anti-inflammatory and antioxidant …
for new antidepressants. Troxerutin, a bioflavonoid with anti-inflammatory and antioxidant …
[HTML][HTML] Containment of neuroimmune challenge by diosgenin confers amelioration of neurochemical and neurotrophic dysfunctions in ketamine-induced …
Inhibition of neuroinflammation through N-methyl-D-aspartate receptor (NMDAR) regulation
can provide normalization of neurochemical homeostasis and neurotrophic support in the …
can provide normalization of neurochemical homeostasis and neurotrophic support in the …
[HTML][HTML] Yeast supplementation potentiates fluoxetine's anti-depressant effect in mice via modulation of oxido-inflammatory, CREB, and MAPK signaling pathways
Introduction The therapeutic potential of yeast in the management of depression is unknown.
Thus, we evaluated the modulatory effect of nutritional yeast supplementation on …
Thus, we evaluated the modulatory effect of nutritional yeast supplementation on …
[PDF][PDF] Current Research in Physiology
A Potokiri, NA Omeiza, AM Ajayi… - Current Research in …, 2024 - researchgate.net
Introduction: The therapeutic potential of yeast in the management of depression is
unknown. Thus, we evaluated the modulatory effect of nutritional yeast supplementation on …
unknown. Thus, we evaluated the modulatory effect of nutritional yeast supplementation on …
[PDF][PDF] Brain Disorders
Inhibition of neuroinflammation through N-methyl-D-aspartate receptor (NMDAR) regulation
can provide normalization of neurochemical homeostasis and neurotrophic support in the …
can provide normalization of neurochemical homeostasis and neurotrophic support in the …