In primary Sjögren syndrome (pSS), chronic inflammation of exocrine glands results in tissue
destruction and sicca symptoms, primarily of the mouth and eyes. Fatigue, arthralgia and …

Primary Sjögren's syndrome (pSS) is considered to be a multifactorial disease, where
underlying genetic predisposition, epigenetic mechanisms and environmental factors …

Background Patients infected with the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), exhibit a wide …

Epigenetic changes during ageing have been characterized by multiple epigenetic clocks
that allow the prediction of chronological age based on methylation status. Despite their …

Primary Sjögren's syndrome (pSS) is a chronic autoimmune rheumatic disease
characterized by inflammation of exocrine glands, mainly salivary and lacrimal glands. In …

Background Fatigue is associated with various chronic inflammatory diseases, but few
studies have focused on its occurrence in psoriasis. Objectives To describe fatigue …

Chronic fatigue, pain and depression are common in patients with primary Sjögren's
syndrome. These phenomena mutually affect each other and have a considerable impact on …

Background/Purpose Primary Sjögren's Syndrome (SS) is characterized by B lymphocyte
hyperactivity with B cell activating factor (BAFF) acting as an important regulator. Single …

Objective To determine the upregulation of IL-21-inducible genes in minor salivary glands
(MSGs) in 28 primary SS (pSS) patients and 12 non-pSS subjects and correlate it with …

Fatigue is a major clinical problem. Finding the right treatment is challenging, as no specific
options exist and only a few of the mechanisms contributing to fatigue are known. Because …