How depressing is inbreeding? A meta-analysis of 30 years of research on the effects of inbreeding in livestock

HP Doekes, P Bijma, JJ Windig - Genes, 2021 - mdpi.com
Inbreeding depression has been widely documented for livestock and other animal and
plant populations. Inbreeding is generally expected to have a stronger unfavorable effect on …

Selection for bull fertility: a review

ML Butler, JM Bormann, RL Weaber… - Translational Animal …, 2020 - academic.oup.com
Fertility is a critically important factor in cattle production because it directly relates to the
ability to produce the offspring necessary to offset costs in production systems. Female …

Inbreeding depression due to recent and ancient inbreeding in Dutch Holstein–Friesian dairy cattle

HP Doekes, RF Veerkamp, P Bijma, G de Jong… - Genetics Selection …, 2019 - Springer
Background Inbreeding decreases animal performance (inbreeding depression), but not all
inbreeding is expected to be equally harmful. Recent inbreeding is expected to be more …

Genetic architecture and lifetime dynamics of inbreeding depression in a wild mammal

MA Stoffel, SE Johnston, JG Pilkington… - Nature …, 2021 - nature.com
Inbreeding depression is ubiquitous, but we still know little about its genetic architecture and
precise effects in wild populations. Here, we combine long-term life-history data with 417 K …

A comparison of marker-based estimators of inbreeding and inbreeding depression

A Caballero, A Fernández, B Villanueva… - Genetics Selection …, 2022 - Springer
Background The availability of genome-wide marker data allows estimation of inbreeding
coefficients (F, the probability of identity-by-descent, IBD) and, in turn, estimation of the rate …

Effect of recent and ancient inbreeding on production and fertility traits in Canadian Holsteins

BO Makanjuola, C Maltecca, F Miglior, FS Schenkel… - BMC genomics, 2020 - Springer
Background Phenotypic performances of livestock animals decline with increasing levels of
inbreeding, however, the noticeable decline known as inbreeding depression, may not be …

Genomic tools for effective conservation of livestock breed diversity

PG Eusebi, A Martinez, O Cortes - Diversity, 2019 - mdpi.com
Human concern about the status of genetic diversity in livestock breeds and their
conservation has increased, as intense selection and reduced population sizes in many …

On the estimation of inbreeding depression using different measures of inbreeding from molecular markers

A Caballero, B Villanueva, T Druet - Evolutionary Applications, 2021 - Wiley Online Library
The inbreeding coefficient (F) of individuals can be estimated from molecular marker data,
such as SNPs, using measures of homozygosity of individual markers or runs of …

An evaluation of inbreeding measures using a whole-genome sequenced cattle pedigree

SW Alemu, NK Kadri, C Harland, P Faux, C Charlier… - Heredity, 2021 - nature.com
The estimation of the inbreeding coefficient (F) is essential for the study of inbreeding
depression (ID) or for the management of populations under conservation. Several methods …

Inbreeding depression and the probability of racing in the Thoroughbred horse

EW Hill, MA Stoffel, BA McGivney… - … of the Royal …, 2022 - royalsocietypublishing.org
Small effective population sizes and active inbreeding can lead to inbreeding depression
due to deleterious recessive mutations exposed in the homozygous state. The …