Infections during pregnancy can seriously damage fetal neurodevelopment by aberrantly
activating the maternal immune system, directly impacting fetal neural cells. Increasing …

Autophagy is a constitutive cellular process of degradation required to maintain homeostasis
and turn over spent organelles and aggregated proteins. For some viruses, the process can …

Virus-infected cells trigger a robust innate immune response and facilitate virus replication.
Here, we review the role of autophagy in virus infection, focusing on both pro-viral and anti …

At present it is well-defined that autophagy is a fundamental process essential for cell life but
its pro-viral and anti-viral role has been stated out with the COVID pandemic. However …

The process of membrane atg8ylation, defined herein as the conjugation of the ATG8 family
of ubiquitin-like proteins to membrane lipids, is beginning to be appreciated in its broader …

Autophagy is an intracellular scavenging mechanism induced to eliminate damaged,
denatured, or senescent macromolecular substances and organelles in the body. The …

Zika virus (ZIKV) is a globally transmitted mosquito-borne pathogen, and no effective
treatment or vaccine is available yet. Lipophagy, a selective autophagy targeting lipid …

Brain abnormalities and congenital malformations have been linked to the circulating strain
of Zika virus (ZIKV) in Brazil since 2016 during the microcephaly outbreak; however, the …

Viral infections of the central nervous system (CNS) cause variable outcomes from acute to
severe neurological sequelae with increased morbidity and mortality. Viral neuroinvasion …

Viral infections of the central nervous system (CNS) often cause worse neurological
outcomes in younger hosts. Throughout childhood, the brain undergoes extensive …