Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides …

CC Willhite, NA Karyakina, RA Yokel… - Critical reviews in …, 2014 - Taylor & Francis
Aluminum (Al) is a ubiquitous substance encountered both naturally (as the third most
abundant element) and intentionally (used in water, foods, pharmaceuticals, and vaccines); …

Natural products against Alzheimer's disease: Pharmaco-therapeutics and biotechnological interventions

A Dey, R Bhattacharya, A Mukherjee… - Biotechnology advances, 2017 - Elsevier
Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease
associated with memory and cognition impairment ultimately leading to death. It is the …

Neurotoxic effects of aluminium exposure as a potential risk factor for Alzheimer's disease

M Dey, RK Singh - Pharmacological Reports, 2022 - Springer
Aluminium is one of the most widely distributed elements of the Earth's crust. Its routine use
has resulted in excessive human exposure and due to the potential neurotoxic effects has …

Oxidative stress and mitochondrial dysfunction in aluminium neurotoxicity and its amelioration: a review

V Kumar, KD Gill - Neurotoxicology, 2014 - Elsevier
Aluminium is light weight and toxic metal present ubiquitously on earth which has gained
considerable attention due to its neurotoxic effects. The widespread use of products made …

Advance of sporadic Alzheimer's disease animal models

L Zhang, C Chen, MSH Mak, J Lu, Z Wu… - Medicinal research …, 2020 - Wiley Online Library
Abstract Alzheimer's disease (AD), the most common form of dementia, is a progressive
neurodegenerative disease. In the past decades, numbers of promising drug candidates …

Boron compounds exhibit protective effects against aluminum-induced neurotoxicity and genotoxicity: In vitro and in vivo study

H Turkez, S Yıldırım, E Sahin, ME Arslan, B Emsen… - Toxics, 2022 - mdpi.com
Genetic, neuropathological and biochemical investigations have revealed meaningful
relationships between aluminum (Al) exposure and neurotoxic and hematotoxic damage …

Ascorbic acid ameliorates behavioural deficits and neuropathological alterations in rat model of Alzheimer's disease

OJ Olajide, EO Yawson, IT Gbadamosi… - Environmental …, 2017 - Elsevier
Exploring the links between neural pathobiology and behavioural deficits in Alzheimer's
disease (AD), and investigating substances with known therapeutic advantages over …

[HTML][HTML] Glucose 6 phosphatase dehydrogenase (G6PD) and neurodegenerative disorders: Mapping diagnostic and therapeutic opportunities

M Tiwari - Genes & diseases, 2017 - Elsevier
Glucose 6 phosphate dehydrogenase (G6PD) is a key and rate limiting enzyme in the
pentose phosphate pathway (PPP). The physiological significance of enzyme is providing …

[HTML][HTML] Differential effect of Ayurvedic nootropics on C. elegans models of Parkinson's disease

J Anjaneyulu, R Vidyashankar, A Godbole - Journal of Ayurveda and …, 2020 - Elsevier
Background Globally, there is increased incidence of Parkinson's Disease (PD), which is the
second most common age-related neurodegenerative disease. The currently available PD …

Phytochemistry and pharmacology of Celastrus paniculatus Wild.: a nootropic drug

M Aleem - Journal of Complementary and Integrative Medicine, 2023 - degruyter.com
Abstract Objectives Celastrus paniculatus Wild is an evergreen climbing shrub. The plant is
of great significance in the traditional Indian System of Medicine, such as Ayurveda, Unani …