Microglia polarization from M1 to M2 in neurodegenerative diseases

S Guo, H Wang, Y Yin - Frontiers in aging neuroscience, 2022 - frontiersin.org
Microglia-mediated neuroinflammation is a common feature of neurodegenerative diseases
such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis …

Microglia-mediated neuroinflammation in neurodegenerative diseases

CS Subhramanyam, C Wang, Q Hu… - Seminars in cell & …, 2019 - Elsevier
Microglia, being the resident immune cells of the central nervous system, play an important
role in maintaining tissue homeostasis and contributes towards brain development under …

Overview of general and discriminating markers of differential microglia phenotypes

AM Jurga, M Paleczna, KZ Kuter - Frontiers in cellular neuroscience, 2020 - frontiersin.org
Inflammatory processes and microglia activation accompany most of the pathophysiological
diseases in the central nervous system. It is proven that glial pathology precedes and even …

Toll-like receptors in immunity and inflammatory diseases: Past, present, and future

K Vijay - International immunopharmacology, 2018 - Elsevier
The immune system is a very diverse system of the host that evolved during evolution to
cope with various pathogens present in the vicinity of environmental surroundings inhabited …

Interferon γ: a master cytokine in microglia-mediated neural network dysfunction and neurodegeneration

O Kann, F Almouhanna, B Chausse - Trends in neurosciences, 2022 - cell.com
Traditionally, lymphocytic interferon γ (IFN-γ) was considered to be a simple'booster'of
proinflammatory responses by microglia (brain-resident macrophages) during bacterial or …

Oligodendrocyte lineage cells and depression

B Zhou, Z Zhu, BR Ransom, X Tong - Molecular psychiatry, 2021 - nature.com
Depression is a common mental illness, affecting more than 300 million people worldwide.
Decades of investigation have yielded symptomatic therapies for this disabling condition but …

The biphasic function of microglia in ischemic stroke

Y Ma, J Wang, Y Wang, GY Yang - Progress in neurobiology, 2017 - Elsevier
Microglia are brain resident macrophages originated from primitive progenitor cells in the
yolk sac. Microglia can be activated within hours and recruited to the lesion site …

[HTML][HTML] A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood

L Steenbergen, R Sellaro, S van Hemert… - Brain, behavior, and …, 2015 - Elsevier
Background: Recent insights into the role of the human microbiota in cognitive and affective
functioning have led to the hypothesis that probiotic supplementation may act as an adjuvant …

Dysmaturation of premature brain: importance, cellular mechanisms, and potential interventions

JJ Volpe - Pediatric neurology, 2019 - Elsevier
Prematurity, especially preterm birth (less than 32 weeks' gestation), is common and
associated with high rates of both survival and neurodevelopmental disability, especially …

Exploring Braak's hypothesis of Parkinson's disease

CD Rietdijk, P Perez-Pardo, J Garssen… - Frontiers in …, 2017 - frontiersin.org
Parkinson's disease (PD) is a neurodegenerative disorder for which there is no cure. Most
patients suffer from sporadic PD, which is likely caused by a combination of genetic and …