Updated international consensus report on the investigation and management of primary immune thrombocytopenia

D Provan, DM Arnold, JB Bussel, BH Chong… - Blood …, 2019 - ashpublications.org
Over the last decade, there have been numerous developments and changes in treatment
practices for the management of patients with immune thrombocytopenia (ITP). This article is …

Eltrombopag for use in children with immune thrombocytopenia

TO Kim, J Despotovic, MP Lambert - Blood advances, 2018 - ashpublications.org
Eltrombopag is currently the only US Food and Drug Administration–approved
thrombopoietin receptor agonist for the treatment of chronic immune thrombocytopenia (ITP) …

Pediatric ITP: is it different from adult ITP?

JM Despotovic, AB Grimes - Hematology 2014, the American …, 2018 - ashpublications.org
Immune thrombocytopenia (ITP) has historically been thought to occur in 2 distinct forms:
childhood ITP and adult ITP. This division is based largely on the presumption that …

Immune thrombocytopenia: a review of upfront treatment strategies

M Kochhar, C Neunert - Blood Reviews, 2021 - Elsevier
Immune thrombocytopenia (ITP), resulting from antibody-mediated platelet destruction
combined with impaired platelet production, is a rare cause of thrombocytopenia in both …

A critical appraisal of the evidence for the role of splenectomy in adults and children with ITP

F Rodeghiero - British journal of haematology, 2018 - Wiley Online Library
In primary chronic immune thrombocytopenia, long‐term response to splenectomy, with 60%
of patients enjoying a treatment‐free life, is higher when compared with rituximab and …

Recommendations for the clinical approach to immune thrombocytopenia: Spanish ITP Working Group (GEPTI)

ME Mingot-Castellano, M Canaro Hirnyk… - Journal of clinical …, 2023 - mdpi.com
Primary immune thrombocytopenia (ITP) is a complex autoimmune disease whose hallmark
is a deregulation of cellular and humoral immunity leading to increased destruction and …

Second‐line treatments in children with immune thrombocytopenia: effect on platelet count and patient‐centered outcomes

RF Grace, KA Shimano, R Bhat… - American journal of …, 2019 - Wiley Online Library
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder with isolated
thrombocytopenia and hemorrhagic risk. While many children with ITP can be safely …

Diagnosis and management of immune thrombocytopenia in childhood

T Kühne - Hämostaseologie, 2017 - thieme-connect.com
Evidence-based medicine is growing in immune thrombocytopenia (ITP), but solid clinical
data are still lacking in many areas. A majority of children has self-limited ITP, but chronic …

Immune thrombocytopenia in children: consensus and controversies

G Singh, D Bansal, NAM Wright - The Indian Journal of Pediatrics, 2020 - Springer
Newly diagnosed immune thrombocytopenia (ITP) is a relatively common disorder of
childhood that does not require an exhaustive laboratory workup for diagnosis. A history and …

Spotlight on eltrombopag in pediatric ITP in China: a long-term observational study in real-world practice

X Cheng, LL Fu, J Ma, H Gu, Z Chen, L Zhao… - Blood …, 2021 - ashpublications.org
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder with isolated
thrombocytopenia and risk of hemorrhage. Treatment with eltrombopag increases and …