Glycyrrhizin: An old weapon against a novel coronavirus

J Chrzanowski, A Chrzanowska… - Phytotherapy …, 2021 - Wiley Online Library
Currently, over 100 countries are fighting against a common enemy, the severe acute
respiratory syndrome coronavirus (SARS‐CoV)‐2, which causes COVID‐19. This has …

Glycyrrhizin as a promising kryptonite against SARS-CoV-2: Clinical, experimental, and theoretical evidences

S Banerjee, SK Baidya, N Adhikari, B Ghosh… - Journal of Molecular …, 2023 - Elsevier
COVID-19 is the most devastating disease in recent times affecting most people globally.
The higher rate of transmissibility and mutations of SARS-CoV-2 along with the lack of …

Carvacrol induced program cell death and cell cycle arrest in androgen-independent human prostate cancer cells via inhibition of notch signaling

F Khan, VK Singh, M Saeed… - Anti-Cancer Agents in …, 2019 - ingentaconnect.com
Background: Several studies have revealed that abnormal activation of Notch signaling is
closely related with the development and progression of prostate cancer. Although there are …

Glycyrrhizic acid inhibits proliferation of gastric cancer cells by inducing cell cycle arrest and apoptosis

H Wang, X Ge, H Qu, N Wang, J Zhou… - Cancer management …, 2020 - Taylor & Francis
Purpose Glycyrrhizic acid (GA) is the main active ingredient extracted from Chinese herb
licorice root, and it shows anti-tumor effects in many cancer types, while its role in gastric …

Hesperidin induces ROS-mediated apoptosis along with cell cycle arrest at G2/M phase in human gall bladder carcinoma

P Pandey, U Sayyed, RK Tiwari, MH Siddiqui… - Nutrition and …, 2019 - Taylor & Francis
A natural predominant flavonoid hesperidin rich in citrus fruits exhibits multifunctional
medicinal properties. The anticancerous potential of hesperidin has been widely explored; …

Nutraceuticals and exercise against muscle wasting during cancer cachexia

G Aquila, AD Re Cecconi, JJ Brault, O Corli, R Piccirillo - Cells, 2020 - mdpi.com
Cancer cachexia (CC) is a debilitating multifactorial syndrome, involving progressive
deterioration and functional impairment of skeletal muscles. It affects about 80% of patients …

Glycyrrhizin mediates downregulation of notch pathway resulting in initiation of apoptosis and disruption in the cell cycle progression in cervical cancer cells

A Ahmad, RK Tiwari, M Saeed, I Ahmad… - Nutrition and …, 2022 - Taylor & Francis
Growing emphasis on exploring the antiproliferative potential of natural compounds has
gathered momentum for the formulation of anticancer drugs. In the present study, the …

[HTML][HTML] Glycyrrhiza, a commonly used medicinal herb: Review of species classification, pharmacology, active ingredient biosynthesis, and synthetic biology

L Wu, T Ma, C Zang, Z Xu, W Sun, H Luo… - Journal of Advanced …, 2024 - Elsevier
Background Licorice is extensively and globally utilized as a medicinal herb and is one of
the traditional Chinese herbal medicines with valuable pharmacological effects. Its …

Neferine, an alkaloid from lotus seed embryo targets HeLa and SiHa cervical cancer cells via pro‐oxidant anticancer mechanism

S Dasari, V Bakthavachalam… - Phytotherapy …, 2020 - Wiley Online Library
Apoptosis and autophagy are important processes that control cellular homeostasis and
have been highlighted as promising targets for novel anticancer drugs. This study aims to …

Glycyrrhizic acid enhances the anticancer activity of cisplatin in the human ovarian cancer cell line

F Omidi, S Shahbazi, S Reiisi, S Azhdari… - Toxicology in Vitro, 2023 - Elsevier
This study aimed to investigate the effects of glycyrrhizic acid (GL) on the anticancer activity
of cisplatin in A2780 ovarian cancer cells. Cultured A2780 cells were treated with different …