Platinum drugs with manifest therapeutic effects are widely used, but their systemic toxicity
and the drug resistance acquired by cancer cells limit their clinical applications. Thus, the …

Both T-cell deprivation and insufficient tumor immunogenicity seriously hinder the efficacy of
immune-mediated tumor destruction in melanoma. In this work, an amphiphilic polyethylene …

Neoadjuvant and adjuvant therapies have made significant progress in cancer treatment.
However, tumor adjuvant therapy still faces challenges due to the intrinsic heterogeneity of …

Prodrug nanoassemblies combine the advantages of prodrug and nanomedicines, offering
great potential in targeting the lesion sites and specific on-demand drug release, maximizing …

Abstract In 2021, The MOE Key Laboratory of Macromolecular Synthesis and
Functionalization in Zhejiang University had achieved several important results. First, a …

Photodynamic therapy (PDT) has emerged as an efficient treatment for cancers in recent
years. However, PDT is limited by low utilization of photosensitizers and tumor hypoxia. The …

Nowadays, destruction of redox homeostasis to induce cancer cell death is an emerging anti‐
cancer strategy. Here, the authors utilized pH‐sensitive acetalated β‐cyclodextrin (Ac‐β …

The complex environment of cisplatin-resistant tumors leads to the failure of currently
available treatments. Therefore, a comprehensive and effective strategy is urgently required …

Chirality is an omnipresent structural feature found in nature. The transfer and amplification
of chirality are widely recognized phenomena. In appropriate solvents, chiral molecules can …

Laryngeal cancer is the most common malignant tumor for which there is still a lack of
effective treatment. Traditional radiotherapy, chemotherapy, and surgery all have significant …