DNA Origami: From Molecular Folding Art to Drug Delivery Technology

Q Jiang, Y Shang, Y Xie, B Ding - Advanced Materials, 2024 - Wiley Online Library
DNA molecules that store genetic information in living creatures can be repurposed as
building blocks to construct artificial architectures, ranging from the nanoscale to the …

Synthetic antigen-conjugated dna systems for antibody detection and characterization

S Ranallo, S Bracaglia, D Sorrentino, F Ricci - ACS sensors, 2023 - ACS Publications
Antibodies are among the most relevant biomolecular targets for diagnostic and clinical
applications. In this Perspective, we provide a critical overview of recent research efforts …

Gene-encoding DNA origami for mammalian cell expression

JA Kretzmann, A Liedl, A Monferrer… - Nature …, 2023 - nature.com
DNA origami may enable more versatile gene delivery applications through its ability to
create custom nanoscale objects with specific targeting, cell-invading, and intracellular …

Optically responsive protein coating of DNA origami for triggered antigen targeting

I Seitz, H Ijäs, V Linko… - ACS Applied Materials & …, 2022 - ACS Publications
DNA nanostructures have emerged as modular building blocks in several research fields
including biomedicine and nanofabrication. Their proneness to degradation in various …

Isothermal self-assembly of multicomponent and evolutive DNA nanostructures

C Rossi-Gendron, F El Fakih, L Bourdon… - Nature …, 2023 - nature.com
Thermal annealing is usually needed to direct the assembly of multiple complementary DNA
strands into desired entities. We show that, with a magnesium-free buffer containing NaCl …

Biomolecule-driven two-factor authentication strategy for access control of molecular devices

X Zhang, Y Liu, B Wang, S Zhou, P Shi, B Cao… - ACS …, 2023 - ACS Publications
The rise of DNA nanotechnology is promoting the development of molecular security
devices and marking an essential change in information security technology, to one that can …

Recent advances in DNA origami-engineered nanomaterials and applications

P Zhan, A Peil, Q Jiang, D Wang, S Mousavi… - Chemical …, 2023 - ACS Publications
DNA nanotechnology is a unique field, where physics, chemistry, biology, mathematics,
engineering, and materials science can elegantly converge. Since the original proposal of …

Fluorescence biosensing based on bifurcated DNA scaffold-aggregated Ag nanocluster via responsive conformation switch of quasi-molecular beacon

J He, X Shang, M Long, C Yang, Y Zhang, M Li… - Analytical …, 2024 - ACS Publications
To address the limitations of typical hairpin-structural molecular beacons, exploring the
ability of a quasi-molecular beacon (q MB) to create label-free fluorescence biosensors is …

Aptamers for viral detection and inhibition

B Chakraborty, S Das, A Gupta, Y Xiong… - ACS infectious …, 2022 - ACS Publications
Recent times have experienced more than ever the impact of viral infections in humans.
Viral infections are known to cause diseases not only in humans but also in plants and …

Recent advancements in design of nucleic acid nanocarriers for controlled drug delivery

RJ Mosley, B Rucci, ME Byrne - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Research of nanoscale nucleic acid carriers has garnered attention in recent years due to
their distinctive and controllable properties. However, current knowledge is limited in how …