Magnetic field effects in biology from the perspective of the radical pair mechanism

H Zadeh-Haghighi, C Simon - Journal of the Royal …, 2022 - royalsocietypublishing.org
Hundreds of studies have found that weak magnetic fields can significantly influence various
biological systems. However, the underlying mechanisms behind these phenomena remain …

[HTML][HTML] Radical pairs may explain reactive oxygen species-mediated effects of hypomagnetic field on neurogenesis

R Rishabh, H Zadeh-Haghighi… - PLOS Computational …, 2022 - journals.plos.org
Exposures to a hypomagnetic field can affect biological processes. Recently, it has been
observed that hypomagnetic field exposure can adversely affect adult hippocampal …

[HTML][HTML] Chronic lithium treatment ameliorates ketamine-induced mania-like behavior via the PI3K-AKT signaling pathway

RJ Ni, TH Gao, YY Wang, Y Tian, JX Wei… - Zoological …, 2022 - ncbi.nlm.nih.gov
Ketamine, a rapid-acting antidepressant drug, has been used to treat major depressive
disorder and bipolar disorder (BD). Recent studies have shown that ketamine may increase …

[HTML][HTML] Entangled radicals may explain lithium effects on hyperactivity

H Zadeh-Haghighi, C Simon - Scientific Reports, 2021 - nature.com
It is known that bipolar disorder and its lithium treatment involve the modulation of oxidative
stress. Moreover, it has been observed that lithium's effects are isotope-dependent. Based …

[HTML][HTML] Radical pairs can explain magnetic field and lithium effects on the circadian clock

H Zadeh-Haghighi, C Simon - Scientific Reports, 2022 - nature.com
Drosophila's circadian clock can be perturbed by magnetic fields, as well as by lithium
administration. Cryptochromes are critical for the circadian clock. Further, the radical pairs in …

[HTML][HTML] Lithium isotopes differentially modify mitochondrial amorphous calcium phosphate cluster size distribution and calcium capacity

ML Deline, J Straub, M Patel, P Subba… - Frontiers in …, 2023 - frontiersin.org
Lithium is commonly prescribed as a mood stabilizer in a variety of mental health conditions,
yet its molecular mode of action is incompletely understood. Many cellular events associated …

Chronic lithium exposure attenuates ketamine-induced mania-like behavior and c-Fos expression in the forebrain of mice

TH Gao, RJ Ni, S Liu, Y Tian, J Wei, L Zhao… - Pharmacology …, 2021 - Elsevier
Ketamine, a dissociative anaesthetic, has been used in the treatment of major depressive
disorder (MDD) as a rapid acting antidepressant drug. Recent studies have shown that …

[HTML][HTML] Calcium imaging reveals depressive-and manic-phase-specific brain neural activity patterns in a murine model of bipolar disorder: a pilot study

M Chen, H Tian, G Huang, T Fang, X Lin, J Shan… - Translational …, 2021 - nature.com
Brain pathological features during manic/hypomanic and depressive episodes in the same
patients with bipolar disorder (BPD) have not been described precisely. The study aimed to …

[PDF][PDF] Biological fractionation of lithium isotopes by cellular Na+/H+ exchangers unravels fundamental transport mechanisms

M Poet, N Vigier, Y Bouret, G Jarretou, R Gautier… - Iscience, 2023 - cell.com
Lithium (Li) has a wide range of uses in science, medicine, and industry, but its isotopy is
underexplored, except in nuclear science and in geoscience. 6 Li and 7 Li isotopic ratio …

Effects of lithium isotopes on sodium/lithium co-transport and calcium efflux through the sodium/calcium/lithium exchanger in mitochondria

I Bukhteeva, FA Rahman, B Kendall… - Frontiers in …, 2024 - frontiersin.org
The effects of lithium (Li) isotopes and their impact on biological processes have recently
gained increased attention due to the significance of Li as a pharmacological agent and the …