Ovarian cancer (OC) is the seventh most commonly diagnosed cancer among women in the
world and the tenth most common in China. Epithelial OC is the most predominant …

Financial Disclosure Prof. Menon has stock ownership and has received research funding
from Abcodia Ltd, a UCL spinout company with an interest in biomarkers and commercial …

To identify common alleles associated with different histotypes of epithelial ovarian cancer
(EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC …

Background: Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy,
responsible for 13 000 deaths per year in the United States. Risk prediction based on …

The lysosome is the final destination for degradation of endocytic cargo, plasma membrane
constituents, and intracellular components sequestered by macroautophagy. Fusion of …

Purpose The aim of this study was to estimate the contribution of deleterious mutations in the
RAD51B, RAD51C, and RAD51D genes to invasive epithelial ovarian cancer (EOC) in the …

Genome-wide association studies (GWAS) have identified 12 epithelial ovarian cancer
(EOC) susceptibility alleles. The pattern of association at these loci is consistent in BRCA1 …

Transcriptome-wide association studies (TWASs), as a practical and prevalent approach for
detecting the associations between genetically regulated genes and traits, are now leading …

We sought to identify susceptibility genes for high-grade serous ovarian cancer (HGSOC) by
performing a transcriptome-wide association study of gene expression and splice junction …

Evidence of a mortality benefit continues to elude ovarian cancer (OC) screening. Data from
the US Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial which used a …