Acyl coenzyme A binding protein (ACBP): An aging‐and disease‐relevant “autophagy checkpoint”

L Montégut, M Abdellatif, O Motiño, F Madeo… - Aging …, 2023 - Wiley Online Library
Acyl coenzyme A binding protein (ACBP), also known as diazepam‐binding inhibitor (DBI),
is a phylogenetically ancient protein present in some eubacteria and the entire eukaryotic …

Design Principles for Immunomodulatory Biomaterials

SA Oluwole, WD Weldu, K Jayaraman… - ACS applied bio …, 2024 - ACS Publications
The immune system is imperative to the survival of all biological organisms. A functional
immune system protects the organism by detecting and eliminating foreign and host …

Acyl-coenzyme a binding protein (ACBP)-a risk factor for cancer diagnosis and an inhibitor of immunosurveillance

L Montégut, P Liu, L Zhao, M Pérez-Lanzón, H Chen… - Molecular Cancer, 2024 - Springer
Background The plasma concentrations of acyl coenzyme A binding protein (ACBP, also
known as diazepam-binding inhibitor, DBI, or 'endozepine') increase with age and obesity …

ACBP/DBI protein neutralization confers autophagy-dependent organ protection through inhibition of cell loss, inflammation, and fibrosis

O Motiño, F Lambertucci… - Proceedings of the …, 2022 - National Acad Sciences
Acyl-coenzyme A (CoA)–binding protein (ACBP), also known as diazepam-binding inhibitor
(DBI), is an extracellular feedback regulator of autophagy. Here, we report that injection of a …

High plasma concentrations of acyl‐coenzyme A binding protein (ACBP) predispose to cardiovascular disease: Evidence for a phylogenetically conserved proaging …

L Montégut, A Joseph, H Chen, M Abdellatif… - Aging …, 2023 - Wiley Online Library
Autophagy defects accelerate aging, while stimulation of autophagy decelerates aging. Acyl‐
coenzyme A binding protein (ACBP), which is encoded by a diazepam‐binding inhibitor …

Inhibition of acyl-CoA binding protein (ACBP) by means of a GABAARγ2-derived peptide

G Anagnostopoulos, E Saavedra, F Lambertucci… - Cell Death & …, 2024 - nature.com
Acyl-CoA binding protein (ACBP) encoded by diazepam binding inhibitor (DBI) is an
extracellular inhibitor of autophagy acting on the gamma-aminobutyric acid A receptor …

Synthesis and Structure Optimization of Star Copolymers as Tunable Macromolecular Carriers for Minimal Immunogen Vaccine Delivery

G Mixová, E Tihlaříková, Y Zhu… - Bioconjugate …, 2024 - ACS Publications
Minimal immunogen vaccines are being developed to focus antibody responses against
otherwise challenging targets, including human immunodeficiency virus (HIV), but …