Coordination of circadian timing in mammals
SM Reppert, DR Weaver - Nature, 2002 - nature.com
Time in the biological sense is measured by cycles that range from milliseconds to years.
Circadian rhythms, which measure time on a scale of 24 h, are generated by one of the most …
Circadian rhythms, which measure time on a scale of 24 h, are generated by one of the most …
Structure and function of DNA photolyase and cryptochrome blue-light photoreceptors
A Sancar - Chemical reviews, 2003 - ACS Publications
Photoreactivation1, 2 is the reversal of the harmful effects, such as growth delay,
mutagenesis, and killing, of far UV (200-300 nm) on organisms by concurrent or subsequent …
mutagenesis, and killing, of far UV (200-300 nm) on organisms by concurrent or subsequent …
Phototransduction by retinal ganglion cells that set the circadian clock
DM Berson, FA Dunn, M Takao - Science, 2002 - science.org
Light synchronizes mammalian circadian rhythms with environmental time by modulating
retinal input to the circadian pacemaker—the suprachiasmatic nucleus (SCN) of the …
retinal input to the circadian pacemaker—the suprachiasmatic nucleus (SCN) of the …
An action spectrum for melatonin suppression: evidence for a novel non‐rod, non‐cone photoreceptor system in humans
K Thapan, J Arendt, DJ Skene - The Journal of physiology, 2001 - Wiley Online Library
1 Non‐image forming, irradiance‐dependent responses mediated by the human eye include
synchronisation of the circadian axis and suppression of pineal melatonin production. The …
synchronisation of the circadian axis and suppression of pineal melatonin production. The …
Mechanisms of DNA Repair by Photolyase and Excision Nuclease (Nobel Lecture).
A Sancar - Angewandte Chemie International Edition, 2016 - search.ebscohost.com
The article presents the result of a study which examined DNA repair through photolyase in
Escherichia coli and nucleotide excision repair in both microorganism and humans. The …
Escherichia coli and nucleotide excision repair in both microorganism and humans. The …
Melanopsin and rod–cone photoreceptive systems account for all major accessory visual functions in mice
In the mammalian retina, besides the conventional rod–cone system, a melanopsin-
associated photoreceptive system exists that conveys photic information for accessory visual …
associated photoreceptive system exists that conveys photic information for accessory visual …
Intrinsically photosensitive retinal ganglion cells
Life on earth is subject to alternating cycles of day and night imposed by the rotation of the
earth. Consequently, living things have evolved photodetective systems to synchronize their …
earth. Consequently, living things have evolved photodetective systems to synchronize their …
Melanopsin (Opn4) Requirement for Normal Light-Induced Circadian Phase Shifting
S Panda, TK Sato, AM Castrucci, MD Rollag… - Science, 2002 - science.org
The master circadian oscillator in the hypothalamic suprachiasmatic nucleus is entrained to
the day/night cycle by retinal photoreceptors. Melanopsin (Opn4), an opsin-based …
the day/night cycle by retinal photoreceptors. Melanopsin (Opn4), an opsin-based …
Time zones: a comparative genetics of circadian clocks
MW Young, SA Kay - Nature Reviews Genetics, 2001 - nature.com
The circadian clock is a widespread cellular mechanism that underlies diverse rhythmic
functions in organisms from bacteria and fungi, to plants and animals. Intense genetic …
functions in organisms from bacteria and fungi, to plants and animals. Intense genetic …
Characterization of an ocular photopigment capable of driving pupillary constriction in mice
RJ Lucas, RH Douglas, RG Foster - Nature neuroscience, 2001 - nature.com
This work demonstrates that transgenic mice lacking both rod and cone photoreceptors
(rd/rd cl) retain a pupillary light reflex (PLR) that does not rely on local iris photoreceptors …
(rd/rd cl) retain a pupillary light reflex (PLR) that does not rely on local iris photoreceptors …