Highlights•Learning induces mitral cell sparsening and pattern decorrelation.•GCs mediate
lateral inhibition to facilitate pattern separation of mitral cells.•Adult-born neurons mediate …

Volatile chemicals in the environment provide ethologically important information to many
animals. However, how animals learn to use this information is only beginning to be …

Pleasant odorants are represented in the posterior olfactory bulb (pOB) in mice. How does
this hedonic information generate odor-motivated behaviors? Using optogenetics, we report …

Microglia play key roles in regulating synapse development and refinement in the
developing brain, but it is unknown whether they are similarly involved during adult …

In a complex and dynamic environment, the brain flexibly adjusts its circuits to preferentially
process behaviorally relevant information. Here, we investigated how the olfactory bulb …

New neurons are continuously generated in the adult brain through a process called adult
neurogenesis. This form of plasticity has been correlated with numerous behavioral and …

The olfactory bulb is a unique site of continuous neurogenesis, primarily generating
inhibitory interneurons, a process that begins at birth and extends through infancy and …

We have developed a spiking neural network (SNN) algorithm for signal restoration and
identification based on principles extracted from the mammalian olfactory system and …

Olfactory perceptual learning is defined as an improvement in the discrimination of
perceptually close odorants after passive exposure to these odorants. In mice, simple …

Adult olfactory neurogenesis provides waves of new neurons involved in memory encoding.
However, how the olfactory bulb deals with neuronal renewal to ensure the persistence of …