Chronic inflammation is the main feature of many long-term inflammatory diseases such as
autoimmune diseases, metabolic disorders, and cancer. There is a growing number of …

A loss of humoral tolerance is a hallmark of many autoimmune diseases and the detection of
self-reactive antibodies (autoantibodies) of the immunoglobulin G (IgG) isotype is widely …

BACKGROUND Nuclear magnetic resonance (NMR) spectra of serum obtained under
quantitative conditions for lipoprotein particle analyses contain additional signals that could …

Fine structural details of glycans attached to the conserved N-glycosylation site significantly
not only affect function of individual immunoglobulin G (IgG) molecules but also mediate …

All immunoglobulin G molecules carry N-glycans, which modulate their biological activity.
Changes in N-glycosylation of IgG associate with various diseases and affect the activity of …

Objective Glycans attached to the Fc portion of IgG are important modulators of IgG effector
functions. Interindividual differences in IgG glycome composition are large and they …

Background Glycosylated proteins partake in multiple cellular processes including
inflammation. We hypothesized that GlycA, a novel biomarker of protein glycan N‐acetyl …

Background Glycobiology is an underexplored research area in inflammatory bowel disease
(IBD), and glycans are relevant to many etiological mechanisms described in IBD …

Staphylococcus aureus bacteremia (SaB) causes significant disease in humans, carrying
mortality rates of∼ 25%. The ability to rapidly predict SaB patient responses and guide …

Glycosylation is one of the most common posttranslational modifications of proteins. It has
important roles for protein structure, stability and functions. In vivo the glycostructures …