A complete temporal transcription factor series in the fly visual system

N Konstantinides, I Holguera, AM Rossi, A Escobar… - Nature, 2022 - nature.com
The brain consists of thousands of neuronal types that are generated by stem cells
producing different neuronal types as they age. In Drosophila, this temporal patterning is …

Coordinated control of neuronal differentiation and wiring by sustained transcription factors

MN Özel, CS Gibbs, I Holguera, M Soliman, R Bonneau… - Science, 2022 - science.org
The large diversity of cell types in nervous systems presents a challenge in identifying the
genetic mechanisms that encode it. Here, we report that nearly 200 distinct neurons in the …

Conserved and novel enhancers in the Aedes aegypti single-minded locus recapitulate embryonic ventral midline gene expression

I Schember, W Reid, G Sterling-Lentsch… - PLoS …, 2024 - journals.plos.org
Transcriptional cis-regulatory modules, eg, enhancers, control the time and location of
metazoan gene expression. While changes in enhancers can provide a powerful force for …

[HTML][HTML] An atlas of the developing drosophila visual system glia and subcellular mRNA localization of transcripts in single cells

AAG Ferreira, C Desplan - BioRxiv, 2023 - ncbi.nlm.nih.gov
Glial cells are essential for proper nervous system development and function. To understand
glial development and function, we comprehensively annotated glial cells in a single-cell …

[图书][B] Three Key Features of Nervous System Development: Circuit Assembly, Glial Cells, and RNA Localization

AAG Ferreira - 2023 - search.proquest.com
Nervous system development involves many different coordinated features. Three of these
features are: circuit assembly, glial cells, and RNA localization. First, to assemble accurate …

[引用][C] Coordinated control of neuronal differentiation and wiring by sustained transcription factors