Solubility limited bioavailability is one of the crucial parameters that affect the formulation
development of the new chemical entities. Thus the major constraint in the pharmaceutical …

Hesperidin is a polyphenol derived from citrus fruits that has a broad potential for biological
activity and the ability to positively modify the intestinal microbiome. However, its activity is …

The method of green technology which is based on supercritical solvent has been studied in
this work for analysis of nanomedicine preparation of solid dosage oral medications. Given …

This study aimed to develop a solid dispersion (SD) of MT-102, a new anti-inflammatory
agent, to improve its oral bioavailability. The ternary SD formulations of MT-102 (a poorly …

The aim was to formulate self-emulsifying drug delivery systems (SEDDS) to hasten
dissolution and oral bioavailability of gliquidone (GLQ) as lipophilic oral hypoglycemic. In …

Aqueous ethanol mixtures of different percentage compositions were used as solvents for
poorly water soluble drug aspirin. Densities of the solutions were measured experimentally …

In this research paper, we explored the predictive capabilities of three different models of
Polynomial Regression (PR), Extreme Gradient Boosting (XGB), and LASSO to estimate the …

This paper presents an investigation into the modeling and prediction of the density of
supercritical carbon dioxide (SC-CO 2) and mole fraction of Erlotinib hydrochloride using …

Background and Aims: Literature reveals many benefits and potentials of the stem bark
extract of Prosopis africana but like other plant extracts, its use in the oral pharmaceutical …

To summarize, our study investigated numerous cellular effects, in vivo toxicity, as well as
osmolality of eleven different polyethylene glycols on Caco-2 cells. Data analysis with …