Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …

Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …

Ischemic stroke (IS) produces a powerful inflammatory cascade in the brain, resulting in the
occurrence of neuroinflammation. Neuroinflammation is triggered not only by resident …

Acute ischaemic and haemorrhagic stroke account for significant disability and morbidity
burdens worldwide. The myeloid arm of the peripheral innate immune system is critical in …

Ischemic stroke is a leading cause of disability and death. It imposes a heavy economic
burden on individuals, families and society. The mortality rate of ischemic stroke has …

Stroke is the second leading cause of death globally and the major cause of long-term
disability. Among the types of strokes, ischemic stroke, which occurs due to obstruction of …

Myeloid cell leukemia‐1 (MCL1), an antiapoptotic member of the BCL2 family characterized
by a short half‐life, functions as a rapid sensor that regulates cell death and other relevant …

Ischemic stroke is major cause of disability and mortality worldwide, and aging is strong risk
factor for poor post-stroke outcome. Neutrophils traffic rapidly to the brain following ischemic …

Background The immune response to acute ischemic stroke (AIS) is implicated in diagnosis,
prognosis, and intervention; however, the temporal dynamics of leukocytes following AIS are …

Therapeutic hypothermia (TH) is a promising neuroprotective agent for treating stroke.
However, its clinical application was limited by the impractical duration. Icariin (ICA) were …