Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism

A Rodríguez, S Ezquerro… - American Journal …, 2015 - journals.physiology.org
Adipose tissue constitutes an extremely active endocrine organ with a network of signaling
pathways enabling the organism to adapt to a wide range of different metabolic challenges …

20 Years with SGBS cells-a versatile in vitro model of human adipocyte biology

D Tews, RE Brenner, R Siebert, KM Debatin… - International Journal of …, 2022 - nature.com
Abstract 20 years ago, we described a human cell strain derived from subcutaneous
adipose tissue of an infant supposed to have Simpson-Golabi-Behmel Syndrome (SGBS) …

Drugs involved in dyslipidemia and obesity treatment: focus on adipose tissue

S Dias, S Paredes, L Ribeiro - International journal of …, 2018 - Wiley Online Library
Metabolic syndrome can be defined as a state of disturbed metabolic homeostasis
characterized by visceral obesity, atherogenic dyslipidemia, arterial hypertension, and …

Comprehensive analysis reveals the potential roles of CDKN3 in pancancer and verification in endometrial cancer

C Gao, X Fan, Y Liu, Y Han, S Liu, H Li… - … Journal of General …, 2023 - Taylor & Francis
Background Cyclin-dependent kinase inhibitor 3 (CDKN3) has been studied in many
cancers. However, the comprehensive and systematic pancancer analysis of CDKN3 genes …

[HTML][HTML] Role of 1α, 25-dihydroxyvitamin D3 in adipogenesis of SGBS cells: new insights into human preadipocyte proliferation

I Felicidade, D Sartori, SLM Coort… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Compared with non-obese individuals, obese individuals commonly store
more vitamin D in adipose tissue. VDR expression in adipose tissue can influence …

Cancer cell metabolism as new targets for novel designed therapies

IM de Mas, E Aguilar, A Jayaraman… - Future medicinal …, 2014 - Taylor & Francis
Metabolic processes are altered in cancer cells, which obtain advantages from this
metabolic reprogramming in terms of energy production and synthesis of biomolecules that …

HBP1 promotes chicken preadipocyte proliferation via directly repressing SOCS3 transcription

H Chen, S Zhou, Y Wang, Q Zhang, L Leng… - International Journal of …, 2024 - Elsevier
Preadipocyte proliferation is an essential process in adipose development. During
proliferation of preadipocytes, transcription factors play crucial roles. HMG-box protein 1 …

Gene expression and characterization of clonally derived murine embryonic brown and brite adipocytes

C Velez‐delValle, CP Hernandez‐Mosqueira… - FEBS Open …, 2024 - Wiley Online Library
White adipocytes store energy, while brown and brite adipocytes release heat via
nonshivering thermogenesis. In this study, we characterized two murine embryonic clonal …

DNA methylation of SSPN is linked to adipose tissue distribution and glucose metabolism

M Keller, M Klös, K Rohde, J Krüger, T Kurze… - The FASEB …, 2018 - Wiley Online Library
ABSTRACT DNA methylation is a crucial epigenetic mechanism in obesity and fat
distribution. We explored the Sarcospan (SSPN) gene locus by using genome‐wide data …

Adipocyte hyperplasia and hypertrophy in the development of Type 2 Diabetes Mellitus

X Gao - 2023 - theses.gla.ac.uk
Increasingly obesity and obesity-induced type 2 diabetes mellitus (T2DM) are becoming
significant societal issues affecting health and longevity in today's world. When the human …