Functional roles of B‐vitamins in the gut and gut microbiome

T Uebanso, T Shimohata, K Mawatari… - Molecular nutrition & …, 2020 - Wiley Online Library
The gut microbiota produce hundreds of bioactive compounds, including B‐vitamins, which
play significant physiological roles in hosts by supporting the fitness of symbiotic species …

[PDF][PDF] Gastrointestinal handling of water-soluble vitamins

HM Said, E Nexo - Compr Physiol, 2018 - researchgate.net
Nine compounds are classified as water-soluble vitamins, eight B vitamins and one vitamin
C. The vitamins are mandatory for the function of numerous enzymes and lack of one or …

Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism

E Belda, L Voland, V Tremaroli, G Falony, S Adriouch… - Gut, 2022 - gut.bmj.com
Objectives Gut microbiota is a key component in obesity and type 2 diabetes, yet
mechanisms and metabolites central to this interaction remain unclear. We examined the …

[HTML][HTML] Inhibition of intestinal ascorbic acid uptake by lipopolysaccharide is mediated via transcriptional mechanisms

VS Subramanian, S Sabui, H Moradi… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Ascorbic acid (AA) accumulation in intestinal epithelial cells is an active transport process
mainly mediated by two sodium-dependent vitamin C transporters (SVCT-1 and SVCT-2). To …

Bacterial lipopolysaccharide inhibits colonic carrier-mediated uptake of thiamin pyrophosphate: roles for TLR4 receptor and NF-κB/P38/JNK signaling pathway

S Anthonymuthu, S Sabui, K Lee… - … of Physiology-Cell …, 2023 - journals.physiology.org
This study investigated the effect of the bacterial endotoxin lipopolysaccharide (LPS) on
colonic uptake of thiamin pyrophosphate (TPP), the biologically active form of vitamin B1 that …

Liver injury, endotoxemia, and their relationship to intestinal microbiota composition in alcohol‐preferring rats

B Posteraro, F Paroni Sterbini, V Petito… - Alcoholism: Clinical …, 2018 - Wiley Online Library
Background There is strong evidence that alcoholism leads to dysbiosis in both humans and
animals. However, it is unclear how changes in the intestinal microbiota (IM) relate to …

[HTML][HTML] Protein Kinase CK2α', More than a Backup of CK2α

M Montenarh, C Götz - Cells, 2023 - mdpi.com
The serine/threonine protein kinase CK2 is implicated in the regulation of fundamental
processes in eukaryotic cells. CK2 consists of two catalytic α or α'isoforms and two …

[HTML][HTML] Unveiling the biogeography and potential functions of the intestinal digesta-and mucosa-associated microbiome of donkeys

R Zhang, J Zhang, W Dang, DM Irwin, Z Wang… - Frontiers in …, 2020 - frontiersin.org
The intestinal microbial composition and metabolic functions under normal physiological
conditions in the donkey are crucial for health and production performance. However …

Gut microbiome and colon cancer: Role of bacterial metabolites and their molecular targets in the host

YD Bhutia, J Ogura, S Sivaprakasam… - Current colorectal cancer …, 2017 - Springer
Abstract Purpose of Review The relationship between colonic bacteria and the host is
symbiotic, but how communication between the two partners occurs is just beginning to be …

Effect of chronic alcohol exposure on gut vitamin B7 uptake: Involvement of epigenetic mechanisms and effect of alcohol metabolites

K Ramamoorthy, S Sabui… - American Journal …, 2021 - journals.physiology.org
Vitamin B7 (biotin) is essential for normal health and its deficiency/suboptimal levels occur in
a variety of conditions including chronic alcoholism. Mammals, including humans, obtain …