BACKGROUND Infertility and pregnancy loss are longstanding problems. Successful
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …

The spermatozoon is a highly differentiated and polarized cell, with two main structures: the
head, containing a haploid nucleus and the acrosomal exocytotic granule, and the flagellum …

Teratozoospermia is usually associated with defective spermiogenesis and is a disorder
with considerable genetic heterogeneity. Although previous studies have identified several …

Male infertility is an important health concern that is expected to have a major genetic
etiology. Although high-throughput sequencing has linked gene defects to more than 50% of …

Teratozoospermia is a common factor associated with male infertility. However,
teratozoospermia characterized by bubble-shaped acrosomes (BSAs) has not yet been …

According to the latest World Health Organization statistics, around 50 to 80 million people
worldwide suffer from infertility, amongst which male factors are responsible for around 20 to …

This brief report concerns the role of human sperm morphology assessment in different
fields of male infertility: basic research, genetics, assisted reproduction technologies …

Purpose Globozoospermia is a genetic syndrome characterized by the presence of round-
headed spermatozoa and infertility due to the inability of these spermatozoa to fertilize the …

Background Large‐and small‐headed sperm are common morphological abnormalities. If
different sperm staining methods affect sperm size, they will make a difference in the …

From a cohort of 167 infertile patients suffering from multiple morphological abnormalities of
the flagellum (MMAF), pathogenic bi-allelic mutations were identified in the CCDC146 gene …