Neuroproteomics, an emerging field at the intersection of neuroscience and proteomics, has
garnered significant attention in the context of neurotrauma research. Neuroproteomics …

Background Metabolic activity alternates between high and low states during different
stages of an organism's life cycle. During the transition from growth to quiescence, a major …

Photoreceptor cells generate neuronal signals in response to capturing light. This process,
called phototransduction, takes place in a highly specialized outer segment organelle. There …

Wheat amylase/trypsin inhibitors (ATIs) have gained significant relevance as inducers of
intestinal and extra-intestinal inflammation. In this study, we present a novel hybrid data …

Background Genetic mutations in α-actinin-4 (ACTN4)—an important actin crosslinking
cytoskeletal protein that provides structural support for kidney podocytes—have been linked …

A primary goal of the US National Cancer Institute's Ras initiative at the Frederick National
Laboratory for Cancer Research is to develop methods to quantify RAS signaling to facilitate …

The GeLC–MS workflow, which combines low-cost, easy-to-use sodium dodecyl sulfate
(SDS)-polyacrylamide gel electrophoresis (SDS-PAGE) with liquid chromatography–mass …

Bottom-up proteomics is a popular approach in molecular biomarker research. However,
protein analysts have realized the limitations of protein-based approaches for identifying …

Inductively coupled plasma–mass spectrometry (ICP–MS) has been widely used in Life
Sciences for the absolute quantification of biomolecules without specific standards …

Recovery from the quiescent developmental stage called dauer is an essential process in C.
elegans and provides an excellent model to understand how metabolic transitions contribute …