Friedelin and 3β-friedelinol: pharmacological activities

MH Radi, RA El-Shiekh, AM El-Halawany… - Revista Brasileira de …, 2023 - Springer
The interest in herbal medicine as a source of drug leads is being reinforced, especially for
tackling challenging therapeutic areas such as antimicrobial resistance, cardiovascular …

Friedelin: Structure, Biosynthesis, Extraction, and Its Potential Health Impact

SK Singh, S Shrivastava, AK Mishra, D Kumar… - Molecules, 2023 - mdpi.com
Pharmaceutical companies are investigating more source matrices for natural bioactive
chemicals. Friedelin (friedelan-3-one) is a pentacyclic triterpene isolated from various plant …

[HTML][HTML] Antibacterial activity of flavonoids and triterpenoids isolated from the stem bark and sap of Staudtia kamerunensis Warb.(Myristicaceae)

JL Tonga, MHK Kamdem, JIM Pagna, TY Fonkui… - Arabian Journal of …, 2022 - Elsevier
The chemical investigation of the ethyl acetate extract of the stem bark of Staudtia
kamerunensis and sap led to the isolation of six compounds which included three …

Four new stilbenes and one new flavonoid with potential antibacterial and anti-SARS-CoV-2 activity from Cajanus cajan

JY Chen, X Lian, YW Fan, ZY Ao, WJ Zhang… - Journal of Natural …, 2023 - Springer
Abstract Four new stilbenes (1–4) and one new flavonoid (5), named cajanines D–H,
together with three known stilbenes (6–8) were isolated from the leaves of Cajanus cajan …

Evaluation of the antibacterial and inhibitory activity of NorA and MepA efflux pumps from Staphylococcus aureus by diosgenin

M do Socorro Costa, ARP da Silva, NJS Araújo… - Life Sciences, 2022 - Elsevier
The increase in bacterial resistance to available antibiotics has driven several researchers
to search for new agents with therapeutic properties. Diosgenin is a naturally occurring …

Self-assembled renewable nano-sized pentacyclic triterpenoid maslinic acids in aqueous medium for anti-leukemic, antibacterial and biocompatibility studies: An …

SN Hasan, J Banerjee, S Patra, S Kar, S Das… - International Journal of …, 2023 - Elsevier
Maslinic acid is a naturally occurring dihydroxy, mono-carboxy bioactive triterpenoid. Its
bulky structure was the main hindrance in the path of biological activity. Sodium and …

Cytotoxic and antimicrobial activities of new phytosteroids from the leaves of Anonidium mannii (Oliv.) Engl. & Diels (Annonaceae)

MHK Kamdem, GP Makoni, KK Silihe, P Jiyane… - South African Journal of …, 2022 - Elsevier
Phytochemical studies of the dichloromethane-methanol (1: 1) extract of the leaves of
Anonidium mannii (Oliv.) Engl. & Diels led to the isolation of two new phytosteroids named …

Synthesis, XRD, spectroscopic (UV–Vis, IR, EPR) and biological evaluations of cobalt (II)-ciprofloxacin complex as antimicrobial agent: In silico molecular docking and …

T Aycan, F Öztürk, T Doruk - Journal of Molecular Structure, 2024 - Elsevier
Abstract Cobalt (II)-Ciprofloxacin complex ([Co (Cip) 2 (H 2 O) 2]. 2 (H 2 PO 4). 8 (H 2 O);
Cip= Ciprofloxacin) containing phosphoric acid was synthesized and its structure was …

Cytotoxic and antibacterial activities of compounds isolated from the fruits and stem-bark of Tetrapleura tetraptera (Schumach. & Thonn.) Taub. (Fabaceae)

MHK Kamdem, GLF Melacheu, KK Silihe… - Medicinal Chemistry …, 2022 - Springer
Abstract A new glyceride, 2, 3-dihydroxypropyl-31-hydroxyhentriacontanoate (1), a new
glucoside stigmasterol derivative, stigmasterol 3-O-β-D-glucopyranoside 6'-hexadecanoate …

[HTML][HTML] Peruranolides A–D, four new withanolides with potential antibacterial and cytotoxic activity from Physalis peruviana L.

QR Li, HJ Liang, BL Li, J Yuan, ZY Ao… - Frontiers in Bioscience …, 2022 - imrpress.com
Background: Many drugs for anti-tumour have been developed, nevertheless, seeking new
anticancer drug is the focus of ongoing investigation. Withanolides have been reported to …