The paper outlines a 2-tier approach for wide-scale biomonitoring programmes. To obtain a
high level of standardization, we suggest the use of caged organisms (mussels or fish). An …

The history of metallothionein (MT) research is reviewed. Various methods for isolation,
characterisation and quantification are evaluated. The role of MT in metal metabolism and …

A spectrophotometric method to evaluate the concentration of metallothioneins in the tissues
of marine organisms has been developed. Metallothionein concentration was evaluated …

Copper has long been known as essential to living systems, in part through its fundamental
role in electron transport and respiration. Over the years into the present, its involvement in …

Inorganic arsenic, a human carcinogen, is enzymatically methylated for detoxication,
consuming S-adenosyl-methionine (SAM) in the process. The fact that DNA …

Cadmium is a human carcinogen that likely acts via epigenetic mechanisms. Since DNA
methylation alterations represent an important epigenetic event linked to cancer, the effect of …

This chapter focuses on a number of enzymes and other proteins that show responses to
pollutants. It provides background information on the nature, function, and biological …

The present study investigated the hepatoprotective role of zinc in attenuating the toxicity
induced by chlorpyrifos in rat liver. Male Sprague–Dawley (SD) rats received either oral …

Eight commercially available organic Zn products and reagent-grade ZnSO4· 7H2O (Zn Sulf)
were evaluated by polarographic analysis, and solubility in. 1 M K2HPO4-KH2PO4 buffer …

It is generally accepted that copper toxicity is a consequence of the generation of reactive
oxygen species (ROS) by copper ions via Fenton or Haber–Weiss reactions. Copper ions …