There is substantial variation between individuals in the immune response to vaccination. In
this review, we provide an overview of the plethora of studies that have investigated factors …

Rotavirus infections are a leading cause of severe, dehydrating gastroenteritis in children< 5
years of age. Despite the global introduction of vaccinations for rotavirus over a decade ago …

Neonates are born with an immature immune system and rely on the transfer of immunity
from their mothers. Maternal antibodies are transferred via the placenta and breast milk …

Background Rotavirus (RV) is the leading cause of diarrhea-related death in children
worldwide and 95% of RV-associated deaths occur in Africa and Asia where RV vaccines …

Oral vaccines are less immunogenic when given to infants in low-income compared with
high-income countries, limiting their potential public health impact. Here, we review factors …

Since its discovery 40 years ago, rotavirus (RV) is considered to be a major cause of infant
and childhood morbidity and mortality particularly in developing countries. Nearly every …

Vaccination is one of medicine's greatest achievements; however, its full potential is
hampered by considerable variation in efficacy across populations and geographical …

Neonatal rotavirus infections are predominantly asymptomatic. While an association with
gastrointestinal symptoms has been described in some settings, factors influencing …

Rotavirus (RV) is the leading cause of diarrhea-related death in children worldwide and
ninety-five percent of rotavirus deaths occur in Africa and Asia. Rotavirus vaccines (RVV) …

There is substantial variation between individuals in the immune response to vaccinations.
The intestinal microbiome plays a crucial rule in the development and regulation of the …