Role of oxidative stress in diabetic cardiomyopathy

B De Geest, M Mishra - Antioxidants, 2022 - mdpi.com
Type 2 diabetes is a redox disease. Oxidative stress and chronic inflammation induce a
switch of metabolic homeostatic set points, leading to glucose intolerance. Several diabetes …

High-density lipoprotein-targeted therapies for heart failure

M Mishra, B De Geest - Biomedicines, 2020 - mdpi.com
The main and common constituents of high-density lipoproteins (HDLs) are apolipoprotein
AI, cholesterol, and phospholipids. Biochemical heterogeneity of HDL particles is based on …

Reconstituted HDL (Milano) treatment efficaciously reverses heart failure with preserved ejection fraction in mice

M Mishra, I Muthuramu, JP Aboumsallem… - International journal of …, 2018 - mdpi.com
Heart failure with preserved ejection fraction (HFpEF) represents a major unmet therapeutic
need. This study investigated whether feeding coconut oil (CC diet) for 26 weeks in female …

Coconut oil aggravates pressure overload-induced cardiomyopathy without inducing obesity, systemic insulin resistance, or cardiac steatosis

I Muthuramu, R Amin, A Postnov, M Mishra… - International Journal of …, 2017 - mdpi.com
Studies evaluating the effects of high-saturated fat diets on cardiac function are most often
confounded by diet-induced obesity and by systemic insulin resistance. We evaluated …

[HTML][HTML] Cholesterol lowering attenuates pressure overload-induced heart failure in mice with mild hypercholesterolemia

I Muthuramu, M Mishra, JP Aboumsallem… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Epidemiological studies support a strong association between non-high-density lipoprotein
cholesterol levels and heart failure incidence. The objective of the current study was to …

Regulation of astrocyte metabolism by mitochondrial translocator protein 18 kDa

W Firth, JL Robb, D Stewart, KR Pye… - Journal of …, 2024 - Wiley Online Library
The mitochondrial translocator protein 18 kDa (TSPO) has been linked to functions from
steroidogenesis to regulation of cellular metabolism and is an attractive therapeutic target for …

The role of mitochondrial translocator protein 18kDa (TSPO) in regulating astrocyte metabolism

W Firth - 2023 - search.proquest.com
Astrocytes, a heterogeneous class of glial cells, play key roles in maintaining homeostasis in
the central nervous system (CNS). This is achieved through multifaceted cellular responses; …

[PDF][PDF] Molecular signatures of myocardial infarction: a multidisciplinary analytical approach

STP Mezger - 2022 - cris.maastrichtuniversity.nl
Myocardial infarction (MI), also known as a heart attack, is the most common cardiovascular
disease (CVD) and the leading cause of death worldwide [1, 305]. A (partial) obstruction of …

Сучасний погляд на ураження серцево-судинної системи при цукровому діабеті і методи їх корекції: фокус на діабетичну кардіоміопатію

ЛВ Журавльова, НВ Сокольнікова, ТА Рогачова - 2020 - repo.knmu.edu.ua
У монографії висвітлено важливі питання патогенезу діабетичної кардіоміопатії та
ураження серцево-судинної системи на тлі цукрового діабету з позицій доказової …

[PDF][PDF] Thérapies ciblant les HDL pour l'insuffisance cardiaque à fraction d'éjection réduite/préservée

B De Geest, M Mishra - VCP Vaisseaux Coeur Poumons, 2020 - lirias.kuleuven.be
La famille des lipoprotéines de haute densité (HDL, high density lipoproteins) se compose
de différentes sous-classes ayant pour éléments constitutifs communs l'apolipoprotéine …