Propionibacterium spp.—source of propionic acid, vitamin B12, and other metabolites important for the industry

K Piwowarek, E Lipińska, E Hać-Szymańczuk… - Applied microbiology …, 2018 - Springer
Bacteria from the Propionibacterium genus consists of two principal groups: cutaneous and
classical. Cutaneous Propionibacterium are considered primary pathogens to humans …

COBALAMIN (COENZYME B12): Synthesis and Biological Significance

JR Roth, JG Lawrence, TA Bobik - Annual review of …, 1996 - annualreviews.org
This review examines deoxyadenosylcobalamin (Ado-B12) biosynthesis, transport, use, and
uneven distribution among living forms. We describe how genetic analysis of enteric …

Genetically engineered whole-cell sensing systems: coupling biological recognition with reporter genes

S Daunert, G Barrett, JS Feliciano, RS Shetty… - Chemical …, 2000 - ACS Publications
A biosensor is a measurement device or system that is composed of a biological sensing
component, which recognizes a chemical or physical change, coupled to a transducing …

A versatile Cas12k-based genetic engineering toolkit (C12KGET) for metabolic engineering in genetic manipulation-deprived strains

Y Cui, H Dong, B Tong, H Wang, X Chen… - Nucleic acids …, 2022 - academic.oup.com
The genetic modification of microorganisms is conducive to the selection of high-yield
producers of high-value-added chemicals, but a lack of genetic tools hinders the …

Recent advances in microbial production of δ-aminolevulinic acid and vitamin B12

Z Kang, J Zhang, J Zhou, Q Qi, G Du, J Chen - Biotechnology advances, 2012 - Elsevier
δ-aminolevulinate (ALA) is an important intermediate involved in tetrapyrrole synthesis
(precursor for vitamin B12, chlorophyll and heme) in vivo. It has been widely applied in …

Production of vitamin B12 in genetically engineered Propionibacterium freudenreichii

Y Piao, M Yamashita, N Kawaraichi, R Asegawa… - Journal of bioscience …, 2004 - Elsevier
Since the chemical synthesis of vitamin B12 requires more than 70 steps, the production of
vitamin B12 has been achieved by microorganism fermentation with additional brief …

Deconvoluting heme biosynthesis to target blood-stage malaria parasites

PA Sigala, JR Crowley, JP Henderson, DE Goldberg - Elife, 2015 - elifesciences.org
Heme metabolism is central to blood-stage infection by the malaria parasite Plasmodium
falciparum. Parasites retain a heme biosynthesis pathway but do not require its activity …

A Novel Pathway for the Biosynthesis of Heme in Archaea: Genome‐Based Bioinformatic Predictions and Experimental Evidence

S Storbeck, S Rolfes, E Raux-Deery, MJ Warren… - …, 2010 - Wiley Online Library
Heme is an essential prosthetic group for many proteins involved in fundamental biological
processes in all three domains of life. In Eukaryota and Bacteria heme is formed via a …

BluB/CobT2 fusion enzyme activity reveals mechanisms responsible for production of active form of vitamin B12 by Propionibacterium freudenreichii

P Deptula, P Kylli, B Chamlagain, L Holm… - Microbial cell …, 2015 - Springer
Background Propionibacterium freudenreichii is a food grade bacterium that has gained
attention as a producer of appreciable amounts of cobalamin, a cobamide with activity of …

[图书][B] Propionibacteria

LI Vorobjeva - 1999 - books.google.com
In a sense, propionic acid bacteria are domesticated bacteria. They might have been used
for cheese making as early as 9000 years Be. In the last 40 years their pmctical uses have …