Challenges with assessing and treating pain in research primates: A focused survey and literature review
EA Paterson, PV Turner - Animals, 2022 - mdpi.com
Simple Summary It is crucial that research primates receive adequate pain treatment from
ethical, animal welfare, and research-related perspectives. There is limited research on …
ethical, animal welfare, and research-related perspectives. There is limited research on …
[图书][B] The laboratory nonhuman primate
JD Fortman, TA Hewett, LC Halliday - 2017 - taylorfrancis.com
Key features Contains 28 updated tables designed as quick, easy-to-use references for New
and Old World species Provides over 100 photographs and illustrations, most now in color …
and Old World species Provides over 100 photographs and illustrations, most now in color …
The history and pharmacology of buprenorphine: New advances in cats
TP Clark - Journal of Veterinary Pharmacology and …, 2022 - Wiley Online Library
Opiates have a long history of medical use as effective analgesics associated with well‐
described side effects, including euphoria, respiratory depression, constipation, bradycardia …
described side effects, including euphoria, respiratory depression, constipation, bradycardia …
Investigating subtle changes in facial expression to assess acute pain in Japanese macaques
VN Gris, N Broche Jr, A Kaneko, M Okamoto… - Scientific Reports, 2022 - nature.com
Abstract Changes in facial expression provide cues for assessing emotional states in
mammals and may provide non-verbal signals of pain. This study uses geometric …
mammals and may provide non-verbal signals of pain. This study uses geometric …
Development and validation of a cynomolgus macaque grimace scale for acute pain assessment
Cynomolgus macaques may undergo surgical procedures for scientific and veterinary
purposes. Recognition and assessment of pain using validated tools is a necessary first step …
purposes. Recognition and assessment of pain using validated tools is a necessary first step …
Lipid bound extended release buprenorphine (high and low doses) and sustained release buprenorphine effectively attenuate post‐operative hypersensitivity in an …
K Navarro, K Jampachaisri, M Huss… - Animal Models and …, 2021 - Wiley Online Library
Background Extended‐release buprenorphine (XR) is indicated for pain management in
rodents, but little is known about its use in mice. This study aimed to investigate whether …
rodents, but little is known about its use in mice. This study aimed to investigate whether …
Evaluation and comparison of pharmacokinetic profiles and safety of two extended-release buprenorphine formulations in common marmosets (Callithrix jacchus)
NJ Fabian, AJ Mannion, M Jamiel, DJ Anderson… - Scientific Reports, 2023 - nature.com
While sustained-release buprenorphine (BSR) is used as a long-lasting opioid analgesic in
common marmosets (Callithrix jacchus), there are no published studies on pharmaceutical …
common marmosets (Callithrix jacchus), there are no published studies on pharmaceutical …
Pharmacokinetic comparison of sustained-release and standard buprenorphine in mice
TS Clark, DD Clark, RF Hoyt - Journal of the American …, 2014 - ingentaconnect.com
Effective pain medication is important for animal stewardship and valid research results. We
compared the pharmacokinetic assessments of standard, immediate-release buprenorphine …
compared the pharmacokinetic assessments of standard, immediate-release buprenorphine …
Clinical efficacy of sustained-release buprenorphine with meloxicam for postoperative analgesia in beagle dogs undergoing ovariohysterectomy
EA Nunamaker, DAF Stolarik, J Ma… - Journal of the …, 2014 - ingentaconnect.com
The goal of the current study was to compare the efficacy, adverse effects, and plasma
buprenorphine concentrations of sustained-release buprenorphine (SRB) and …
buprenorphine concentrations of sustained-release buprenorphine (SRB) and …
Prediction of drug–drug interactions between opioids and overdosed benzodiazepines using physiologically based pharmacokinetic (PBPK) modeling and simulation
Background Researchers have long been interested in the potential drug–drug interactions
(DDIs) between opioids and benzodiazepines. However, much remains unknown …
(DDIs) between opioids and benzodiazepines. However, much remains unknown …