Challenges with assessing and treating pain in research primates: A focused survey and literature review

EA Paterson, PV Turner - Animals, 2022 - mdpi.com
Simple Summary It is crucial that research primates receive adequate pain treatment from
ethical, animal welfare, and research-related perspectives. There is limited research on …

[图书][B] The laboratory nonhuman primate

JD Fortman, TA Hewett, LC Halliday - 2017 - taylorfrancis.com
Key features Contains 28 updated tables designed as quick, easy-to-use references for New
and Old World species Provides over 100 photographs and illustrations, most now in color …

The history and pharmacology of buprenorphine: New advances in cats

TP Clark - Journal of Veterinary Pharmacology and …, 2022 - Wiley Online Library
Opiates have a long history of medical use as effective analgesics associated with well‐
described side effects, including euphoria, respiratory depression, constipation, bradycardia …

Investigating subtle changes in facial expression to assess acute pain in Japanese macaques

VN Gris, N Broche Jr, A Kaneko, M Okamoto… - Scientific Reports, 2022 - nature.com
Abstract Changes in facial expression provide cues for assessing emotional states in
mammals and may provide non-verbal signals of pain. This study uses geometric …

Development and validation of a cynomolgus macaque grimace scale for acute pain assessment

EA Paterson, CI O'Malley, C Moody, S Vogel… - Scientific reports, 2023 - nature.com
Cynomolgus macaques may undergo surgical procedures for scientific and veterinary
purposes. Recognition and assessment of pain using validated tools is a necessary first step …

Lipid bound extended release buprenorphine (high and low doses) and sustained release buprenorphine effectively attenuate post‐operative hypersensitivity in an …

K Navarro, K Jampachaisri, M Huss… - Animal Models and …, 2021 - Wiley Online Library
Background Extended‐release buprenorphine (XR) is indicated for pain management in
rodents, but little is known about its use in mice. This study aimed to investigate whether …

Evaluation and comparison of pharmacokinetic profiles and safety of two extended-release buprenorphine formulations in common marmosets (Callithrix jacchus)

NJ Fabian, AJ Mannion, M Jamiel, DJ Anderson… - Scientific Reports, 2023 - nature.com
While sustained-release buprenorphine (BSR) is used as a long-lasting opioid analgesic in
common marmosets (Callithrix jacchus), there are no published studies on pharmaceutical …

Pharmacokinetic comparison of sustained-release and standard buprenorphine in mice

TS Clark, DD Clark, RF Hoyt - Journal of the American …, 2014 - ingentaconnect.com
Effective pain medication is important for animal stewardship and valid research results. We
compared the pharmacokinetic assessments of standard, immediate-release buprenorphine …

Clinical efficacy of sustained-release buprenorphine with meloxicam for postoperative analgesia in beagle dogs undergoing ovariohysterectomy

EA Nunamaker, DAF Stolarik, J Ma… - Journal of the …, 2014 - ingentaconnect.com
The goal of the current study was to compare the efficacy, adverse effects, and plasma
buprenorphine concentrations of sustained-release buprenorphine (SRB) and …

Prediction of drug–drug interactions between opioids and overdosed benzodiazepines using physiologically based pharmacokinetic (PBPK) modeling and simulation

B Ji, S Liu, Y Xue, X He, VH Man, XQ Xie, J Wang - Drugs in R&D, 2019 - Springer
Background Researchers have long been interested in the potential drug–drug interactions
(DDIs) between opioids and benzodiazepines. However, much remains unknown …