Cardiovascular Regulation in Mice Lacking α2-Adrenergic Receptor Subtypes b and c
RE Link, K Desai, L Hein, ME Stevens, A Chruscinski… - Science, 1996 - science.org
α2-Adrenergic receptors (α2ARs) are essential components of the neural circuitry regulating
cardiovascular function. The role of specific α2AR subtypes (α2a, α2b, and α2c) was …
cardiovascular function. The role of specific α2AR subtypes (α2a, α2b, and α2c) was …
Subtypes of functional α1-and α2-adrenoceptors
JR Docherty - European journal of pharmacology, 1998 - Elsevier
In this review, subtypes of functional α1-and α2-adrenoceptors are discussed. These are cell
membrane receptors, belonging to the seven transmembrane spanning G-protein-linked …
membrane receptors, belonging to the seven transmembrane spanning G-protein-linked …
Selective antagonism of the antinociceptive effect of intrathecally applied alpha adrenergic agonists by intrathecal prazosin and intrathecal yohimbine.
JR Howe, JY Wang, TL Yaksh - Journal of Pharmacology and Experimental …, 1983 - ASPET
We have attempted to define the alpha adrenoceptor subtype (s) on which intrathecally
applied alpha adrenergic agonists act to produce their antinociceptive effect. The potencies …
applied alpha adrenergic agonists act to produce their antinociceptive effect. The potencies …
In situ analysis of alpha-adrenoceptors on arteriolar and venular smooth muscle in rat skeletal muscle microcirculation.
JE Faber - Circulation Research, 1988 - Am Heart Assoc
The purpose of this study was to determine whether both alpha 1-and alpha 2-adrenergic
receptors exist on vascular smooth muscle of microvessels and whether adrenergic …
receptors exist on vascular smooth muscle of microvessels and whether adrenergic …
. alpha. 2 Adrenoceptors: classification, localization, mechanisms and targets for drugs
PB Timmermans, PA Van Zwieten - Journal of medicinal chemistry, 1982 - ACS Publications
The concept of pre-and postjunctionally located a adrenoceptors, as well as the more recent
subdivision into ax and a2 subtypes, has initiated duringthe last decade a renaissance of …
subdivision into ax and a2 subtypes, has initiated duringthe last decade a renaissance of …
α-Adrenoceptor subclassification
K Starke - … , Biochemistry and Pharmacology, Volume 88: Volume …, 2005 - Springer
In this review the classification of a-adrenoceptors into two major subgroups is discussed, an
idea which derived primarily from studies on the pre-and postsynaptic a-receptors at …
idea which derived primarily from studies on the pre-and postsynaptic a-receptors at …
Evidence for more than one type of post-junctional alpha-adrenoceptor.
JC McGrath - Biochemical pharmacology, 1982 - europepmc.org
The concept of two types of alpha-adrenoceptor, alpha 1 located on smooth muscle and
mediating contraction and alpha 2 located on nerve terminals and mediating inhibition of …
mediating contraction and alpha 2 located on nerve terminals and mediating inhibition of …
Distribution and function of peripheral α-adrenoceptors in the cardiovascular system
RR Ruffolo Jr - Pharmacology Biochemistry and Behavior, 1985 - Elsevier
Abstract α-Adrenoceptors may be subdivided based on their anatomical distribution within
the synapse. Presynaptic α-adrenoceptors are generally of the α 2-subtype and modulate …
the synapse. Presynaptic α-adrenoceptors are generally of the α 2-subtype and modulate …
A comparison of pre-and post-junctional potencies of several alpha-adrenoceptor agonists in the cardiovascular system and anococcygeus muscle of the rat …
JR Docherty, JC McGrath - Naunyn-Schmiedeberg's Archives of …, 1980 - Springer
The pre-and post-junctional effects of five α-adrenoceptor agonist drugs were examined in
the pithed rat. On pre-junctional receptors on the cardioac-celerator nerves, oxymetazoline …
the pithed rat. On pre-junctional receptors on the cardioac-celerator nerves, oxymetazoline …
Enhancement of alpha-1 and alpha-2 adrenergic agonist-induced vasoconstriction by removal of endothelium in rat aorta.
GO Carrier, RE White - Journal of Pharmacology and Experimental …, 1985 - ASPET
It is well known that the vascular endothelial cell layer plays an essential role in the
vasodilatory response of several agents. In this study we have investigated the possibility …
vasodilatory response of several agents. In this study we have investigated the possibility …