Neutrophil dynamics in pulmonary fibrosis: Pathophysiological and therapeutic perspectives
LE Crowley, RA Stockley, DR Thickett… - European …, 2024 - publications.ersnet.org
The shared pathobiological mechanisms driving progressive fibrosis in interstitial lung
diseases (ILDs) remain unclear. Neutrophils, the most common immune cells in the human …
diseases (ILDs) remain unclear. Neutrophils, the most common immune cells in the human …
Emerging therapeutic strategies targeting extracellular histones for critical and inflammatory diseases: an updated narrative review
T Yang, J Peng, Z Zhang, Y Chen, Z Liu… - Frontiers in …, 2024 - frontiersin.org
Extracellular histones are crucial damage-associated molecular patterns involved in the
development and progression of multiple critical and inflammatory diseases, such as sepsis …
development and progression of multiple critical and inflammatory diseases, such as sepsis …
Dissecting the role of platelet-derived transforming growth factor-β1 in pulmonary fibrosis
Cellular sources of transforming growth factor-β1 (TGFβ1), a key profibrotic mediator, in
pulmonary fibrosis (PF) remain unclear, although alveolar macrophages and fibroblasts …
pulmonary fibrosis (PF) remain unclear, although alveolar macrophages and fibroblasts …
Caspase-11/GSDMD contributes to the progression of hyperuricemic nephropathy by promoting NETs formation
F Wu, C Chen, G Lin, C Wu, J Xie, K Lin, X Dai… - Cellular and Molecular …, 2024 - Springer
Hyperuricemia is an independent risk factor for chronic kidney disease (CKD) and promotes
renal fibrosis, but the underlying mechanism remains largely unknown. Unresolved …
renal fibrosis, but the underlying mechanism remains largely unknown. Unresolved …
Reply to Chong et al.: Investigating TGFβ1 biological activities using genetically engineered mouse strains
DR Riehl, A Sharma, J Roewe, C Reinhardt… - Proceedings of the …, 2024 - pnas.org
In their letter (1), Chong et al. informed us about their research (2), which thematically
overlaps with figure 4 of our investigation on the role of extracellular histones in the …
overlaps with figure 4 of our investigation on the role of extracellular histones in the …
Disruption of the C5a/C5aR1 axis confers protection against hookworm infection in lung
S Walachowski, L Garo, A Sharma… - Frontiers in …, 2024 - frontiersin.org
Hookworms are soil-transmitted parasitic nematodes that penetrate the host skin before
migrating to the lungs. With an estimated 500-700 million people infected worldwide …
migrating to the lungs. With an estimated 500-700 million people infected worldwide …
Glycolysis and beyond in glucose metabolism: exploring pulmonary fibrosis at the metabolic crossroads
Y Wang, X Wang, C Du, Z Wang, J Wang… - Frontiers in …, 2024 - frontiersin.org
At present, pulmonary fibrosis (PF) is a prevalent and irreversible lung disease with limited
treatment options, and idiopathic pulmonary fibrosis (IPF) is one of its most common forms …
treatment options, and idiopathic pulmonary fibrosis (IPF) is one of its most common forms …
The immunomodulatory of interleukin-33 in rheumatoid arthritis: A systematic review
R Liu, F Wang, X Luo, F Yang, J Gao, H Shen… - Clinical …, 2024 - Elsevier
Rheumatoid arthritis (RA) is a systemic chronic autoimmune disease that primarily affects
the joints and surrounding soft tissues, characterized by chronic inflammation and …
the joints and surrounding soft tissues, characterized by chronic inflammation and …
Advances in understanding the role of interleukins in pulmonary fibrosis
Y He, X Shen, K Zhai, S Nian - Experimental and …, 2024 - spandidos-publications.com
Pulmonary fibrosis (PF) is a progressive, irreversible disease characterized by
heterogeneous interstitial lung tissue damage. It originates from persistent or repeated lung …
heterogeneous interstitial lung tissue damage. It originates from persistent or repeated lung …
Identification of key mitochondria-related genes and their potential crosstalk role with immune pattern in Idiopathic pulmonary fibrosis
J Huang, X Wang, Y Zeng, H Xu, S Zhang, Z Ding… - Gene, 2024 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) stands out as a life-threatening and one of
the most severe interstitial lung diseases. The pathogenesis of IPF is not fully understood …
the most severe interstitial lung diseases. The pathogenesis of IPF is not fully understood …