The fungal plasma membrane is organized into specialized domains that vary in size,
stability, and composition. Membrane compartment of Can1 (MCC)/eisosome domains that …

Human protein kinase C (PKC) isoforms have been implicated in diseases such as
Alzheimer's, diabetes and cancers. In contrast to mammals, which have at least nine genes …

Aspergillus fumigatus is a saprophytic fungus that can cause a variety of human diseases
known as aspergillosis. Mycotoxin gliotoxin (GT) production is important for its virulence and …

The plasma membrane (PM) performs a plethora of physiological processes, the
coordination of which requires spatial and temporal organization into specialized domains of …

Fungal pathogens use various mechanisms to survive exposure to drugs. Prolonged
treatment very often leads to the stepwise acquisition of resistance. The limited number of …

There is growing appreciation that the plasma membrane orchestrates a diverse array of
functions by segregating different activities into specialized domains that vary in size …

The cell wall integrity (CWI) MAPK pathway of budding yeast Saccharomyces cerevisiae is
specialized in responding to cell wall damage, but ongoing research shows that it …

To grow, eukaryotic cells must expand by inserting glycerolipids, sphingolipids, sterols, and
proteins into their plasma membrane, and maintain the proper levels and bilayer distribution …

The survival of eukaryotic organisms during environmental changes is largely dependent on
the adaptive responses elicited by signal transduction cascades, including those regulated …

Eisosomes are lipid domains of the yeast plasma membrane that share similarities to
caveolae of higher eukaryotes. Eisosomes harbor APC-type nutrient transporters for reasons …