One of the major challenges of cardiovascular primary prevention approach is the absence
of early biomarkers of endothelial dysfunction which may be useful for identifying at-risk …

The complex pathobiology underlying cardiovascular diseases (CVDs) has yet to be
explained. Aberrant epigenetic changes may result from alterations in enzymatic activities …

Background Atherosclerosis (AS) is the basis of diabetic macrovascular complications. The
plasma low-density lipoprotein (LDL) particles transcytosis across endothelial cells (ECs) …

Epigenetic mechanisms represent potential molecular routes which could bridge the gap
between genetic background and environmental risk factors contributing to the …

Cardiometabolic diseases (CMDs) are currently the leading cause of death and disability
worldwide, and their underlying regulatory mechanisms remain largely unknown. N6 …

Heart failure (HF) management is challenging due to high clinical heterogeneity of this
disease which makes patients responding differently to evidence-based standard therapy …

Epidemiological evidence shows that diabetic patients have an increased cancer risk and a
higher mortality rate. Glucose could play a central role in metabolism and growth of many …

Despite impressive efforts invested in epigenetic research in the last 50 years, clinical
applications are still lacking. Only a few university hospital centers currently use epigenetic …

The rapid increase in obesity, metabolic syndrome, and cardiovascular diseases (CVDs)
has been related to the rise in sugar-added foods and sweetened beverages consumption …

Diabetes mellitus (DM) is a first-line priority among the problems facing medical science and
public health in almost all countries of the world. The main problem of DM is the high …