The role of serotonin in drug use and addiction
CP Müller, JR Homberg - Behavioural brain research, 2015 - Elsevier
The use of psychoactive drugs is a wide spread behaviour in human societies. The
systematic use of a drug requires the establishment of different drug use-associated …
systematic use of a drug requires the establishment of different drug use-associated …
Contributions of serotonin in addiction vulnerability
Abstract The serotonin (5-hydroxytryptamine; 5-HT) system has long been associated with
mood and its dysregulation implicated in the pathophysiology of mood and anxiety …
mood and its dysregulation implicated in the pathophysiology of mood and anxiety …
Methylenedioxymethamphetamine (MDMA): Serotonergic and dopaminergic mechanisms related to its use and misuse
S Schenk, Q Highgate - Journal of Neurochemistry, 2021 - Wiley Online Library
Methylenedioxymethamphetamine (MDMA) is an amphetamine analogue that preferentially
stimulates the release of serotonin (5HT) and results in relatively small increases in synaptic …
stimulates the release of serotonin (5HT) and results in relatively small increases in synaptic …
MDMA: interactions with other psychoactive drugs
WMY Mohamed, SB Hamida, JC Cassel… - Pharmacology …, 2011 - Elsevier
3, 4-Methylenedioxymethamphetamine (MDMA, ecstasy) is one of the most widely abused
illegal drugs. Some users self-report euphoria and an increased perception and feeling of …
illegal drugs. Some users self-report euphoria and an increased perception and feeling of …
Methylenedioxymethamphetamine (MDMA) in psychiatry: pros, cons, and suggestions
S Schenk, D Newcombe - Journal of Clinical …, 2018 - journals.lww.com
Background For a number of mental health disorders, including posttraumatic stress
disorders (PTSD), there are not many available treatment options. Recently, there has been …
disorders (PTSD), there are not many available treatment options. Recently, there has been …
Acquisition of MDMA self‐administration: pharmacokinetic factors and MDMA‐induced serotonin release
S Bradbury, J Bird, J Colussi‐Mas, M Mueller… - Addiction …, 2014 - Wiley Online Library
The current study aimed to elucidate the role of pharmacokinetic (PK) parameters and
neurotransmitter efflux in explaining variability in (±) 3, 4‐methylenedioxymethamphetamine …
neurotransmitter efflux in explaining variability in (±) 3, 4‐methylenedioxymethamphetamine …
Neurochemical and neurotoxic effects of MDMA (ecstasy) and caffeine after chronic combined administration in mice
AM Górska, K Kamińska, A Wawrzczak-Bargieła… - Neurotoxicity …, 2018 - Springer
Abstract MDMA (3, 4-methylenedioxymethamphetamine) is a psychostimulant popular as a
recreational drug because of its effect on mood and social interactions. MDMA acts at …
recreational drug because of its effect on mood and social interactions. MDMA acts at …
Contribution of impulsivity and novelty‐seeking to the acquisition and maintenance of MDMA self‐administration
J Bird, S Schenk - Addiction biology, 2013 - Wiley Online Library
It has been suggested that the response to novelty and impulsivity predict the latency to
acquisition and maintenance of drug self‐administration, respectively. The aim of this study …
acquisition and maintenance of drug self‐administration, respectively. The aim of this study …
MDMA (“ecstasy”) abuse as an example of dopamine neuroplasticity
S Schenk - Neuroscience & biobehavioral reviews, 2011 - Elsevier
A number of reviews have focused on the short-and long-term effects of MDMA and, in
particular, on the persistent deficits in serotonin neurotransmission that accompany some …
particular, on the persistent deficits in serotonin neurotransmission that accompany some …
Repeated MDMA administration increases MDMA-produced locomotor activity and facilitates the acquisition of MDMA self-administration: role of dopamine D2 …
R van de Wetering, S Schenk - Psychopharmacology, 2017 - Springer
Rationale Repeated exposure to±3, 4-methylenedioxymethamphetamine (MDMA) produces
sensitization to MDMA-produced hyperactivity, but the mechanisms underlying the …
sensitization to MDMA-produced hyperactivity, but the mechanisms underlying the …