Neutrophil extracellular traps (NETs) and damage‐associated molecular patterns (DAMPs): two potential targets for COVID‐19 treatment
S Cicco, G Cicco, V Racanelli… - Mediators of …, 2020 - Wiley Online Library
COVID‐19 is a pandemic disease caused by the new coronavirus SARS‐CoV‐2 that mostly
affects the respiratory system. The consequent inflammation is not able to clear viruses. The …
affects the respiratory system. The consequent inflammation is not able to clear viruses. The …
Update I. A systematic review on the efficacy and safety of chloroquine/hydroxychloroquine for COVID-19
A Cortegiani, M Ippolito, G Ingoglia, P Iozzo… - Journal of critical …, 2020 - Elsevier
Purpose To assess efficacy and safety of chloroquine (CQ)/hydroxychloroquine (HCQ) for
treatment or prophylaxis of COVID-19 in adult humans. Materials and methods MEDLINE …
treatment or prophylaxis of COVID-19 in adult humans. Materials and methods MEDLINE …
Outcomes of 3,737 COVID-19 patients treated with hydroxychloroquine/azithromycin and other regimens in Marseille, France: A retrospective analysis
Background In our institute in Marseille, France, we initiated early and massive screening for
coronavirus disease 2019 (COVID-19). Hospitalization and early treatment with …
coronavirus disease 2019 (COVID-19). Hospitalization and early treatment with …
[HTML][HTML] Treatment of SARS-CoV-2 with high dose oral zinc salts: A report on four patients
E Finzi - International Journal of Infectious Diseases, 2020 - Elsevier
Abstract Coronavirus 2019 (COVID-19) is a pandemic with substantial mortality and no
accepted therapy. We report here on four consecutive outpatients with clinical characteristics …
accepted therapy. We report here on four consecutive outpatients with clinical characteristics …
[HTML][HTML] COVID-19 outpatients: early risk-stratified treatment with zinc plus low-dose hydroxychloroquine and azithromycin: a retrospective case series study
R Derwand, M Scholz, V Zelenko - International journal of antimicrobial …, 2020 - Elsevier
The aim of this study was to describe the outcomes of patients with coronavirus disease
2019 (COVID-19) in the outpatient setting after early treatment with zinc, low-dose …
2019 (COVID-19) in the outpatient setting after early treatment with zinc, low-dose …
Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry
G Simmons, DN Gosalia… - Proceedings of the …, 2005 - National Acad Sciences
Severe acute respiratory syndrome (SARS) is caused by an emergent coronavirus (SARS-
CoV), for which there is currently no effective treatment. SARS-CoV mediates receptor …
CoV), for which there is currently no effective treatment. SARS-CoV mediates receptor …
Early outpatient treatment of symptomatic, high-risk COVID-19 patients that should be ramped up immediately as key to the pandemic crisis
HA Risch - American journal of epidemiology, 2020 - academic.oup.com
More than 1.6 million Americans have been infected with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), and more than 10 times that number carry antibodies to it …
coronavirus 2 (SARS-CoV-2), and more than 10 times that number carry antibodies to it …
Quest for a COVID-19 cure by repurposing small-molecule drugs: mechanism of action, clinical development, synthesis at scale, and outlook for supply
C De Savi, DL Hughes, L Kvaerno - Organic Process Research & …, 2020 - ACS Publications
The outbreak of the COVID-19 pandemic has spurred an intense global effort to repurpose
existing approved drugs for its treatment. In this review, we highlight the development of …
existing approved drugs for its treatment. In this review, we highlight the development of …
Role of endolysosomes in severe acute respiratory syndrome coronavirus-2 infection and coronavirus disease 2019 pathogenesis: implications for potential …
N Khan, X Chen, JD Geiger - Frontiers in pharmacology, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an enveloped, single-
stranded RNA virus. Humans infected with SARS-CoV-2 develop a disease known as …
stranded RNA virus. Humans infected with SARS-CoV-2 develop a disease known as …
Clinical efficacy of chloroquine derivatives in COVID-19 infection: comparative meta-analysis between the big data and the real world
In the context of the current coronavirus disease 2019 (COVID-19) pandemic, we conducted
a meta-analysis on the effects of chloroquine derivatives in patients, based on unpublished …
a meta-analysis on the effects of chloroquine derivatives in patients, based on unpublished …