Anthropometric and adiposity indicators and risk of type 2 diabetes: systematic review and dose-response meta-analysis of cohort studies

A Jayedi, S Soltani, SZ Motlagh, A Emadi, H Shahinfar… - Bmj, 2022 - bmj.com
Objective To present a comprehensive review of the association between measures of body
weight, waist, and fat, and different ratios of these measures, and the risk of type 2 diabetes …

Obesity-induced changes in adipose tissue microenvironment and their impact on cardiovascular disease

JJ Fuster, N Ouchi, N Gokce, K Walsh - Circulation research, 2016 - Am Heart Assoc
Obesity is causally linked with the development of cardiovascular disorders. Accumulating
evidence indicates that cardiovascular disease is the collateral damage of obesity-driven …

The β3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans

BS Finlin, H Memetimin, B Zhu… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Beige adipose tissue is associated with improved glucose homeostasis in
mice. Adipose tissue contains β3-adrenergic receptors (β3-ARs), and this study was …

Adipocytokines in obesity and metabolic disease

H Cao - Journal of endocrinology, 2014 - joe.bioscientifica.com
The current global obesity pandemic is the leading cause for the soaring rates of metabolic
diseases, especially diabetes, cardiovascular disease, hypertension, and non-alcoholic …

From leptin to other adipokines in health and disease: facts and expectations at the beginning of the 21st century

M Blüher, CS Mantzoros - Metabolism, 2015 - Elsevier
This year marks the 20th anniversary of the discovery of leptin, which has tremendously
stimulated translational obesity research. The discovery of leptin has led to realizations that …

Mechanisms of glucocorticoid-induced insulin resistance: focus on adipose tissue function and lipid metabolism

EB Geer, J Islam, C Buettner - Endocrinology and Metabolism …, 2014 - endo.theclinics.com
Mechanisms of Glucocorticoid-Induced Insulin Resistance - Endocrinology and Metabolism
Clinics Skip to Main Content Skip to Main Menu Advertisement Endocrinology and …

The role of adiponectin in cancer: a review of current evidence

M Dalamaga, KN Diakopoulos… - Endocrine …, 2012 - academic.oup.com
Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

Effect of alcohol consumption on biological markers associated with risk of coronary heart disease: systematic review and meta-analysis of interventional studies

SE Brien, PE Ronksley, BJ Turner, KJ Mukamal… - Bmj, 2011 - bmj.com
Objective To systematically review interventional studies of the effects of alcohol
consumption on 21 biological markers associated with risk of coronary heart disease in …

Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome

E Maury, SM Brichard - Molecular and cellular endocrinology, 2010 - Elsevier
Obesity plays a causative role in the pathogenesis of the metabolic syndrome. Adipokines
may link obesity to its co-morbidities. Most adipokines with pro-inflammatory properties are …

Adiponectin levels and risk of type 2 diabetes: a systematic review and meta-analysis

S Li, HJ Shin, EL Ding, RM van Dam - Jama, 2009 - jamanetwork.com
Context The association of obesity with development of type 2 diabetes may be partly
mediated by altered secretion of adipokines by adipose tissue. Greater adiposity down …