Moving protons and electrons in biomimetic systems
An enormous variety of biological redox reactions are accompanied by changes in proton
content at enzyme active sites, in their associated cofactors, in substrates and/or products …
content at enzyme active sites, in their associated cofactors, in substrates and/or products …
[HTML][HTML] Reaction dynamics and proton coupled electron transfer: Studies of tyrosine-based charge transfer in natural and biomimetic systems
BA Barry - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2015 - Elsevier
In bioenergetic reactions, electrons are transferred long distances via a hopping
mechanism. In photosynthesis and DNA synthesis, the aromatic amino acid residue …
mechanism. In photosynthesis and DNA synthesis, the aromatic amino acid residue …
Specific metallo-protein interactions and antimicrobial activity in Histatin-5, an intrinsically disordered salivary peptide
Abstract Histatin-5 (Hst-5) is an antimicrobial, salivary protein that is involved in the host
defense system. Hst-5 has been proposed to bind functionally relevant zinc and copper but …
defense system. Hst-5 has been proposed to bind functionally relevant zinc and copper but …
A tyrosine–tryptophan dyad and radical-based charge transfer in a ribonucleotide reductase-inspired maquette
In class 1a ribonucleotide reductase (RNR), a substrate-based radical is generated in the α2
subunit by long-distance electron transfer involving an essential tyrosyl radical (Y122O·) in …
subunit by long-distance electron transfer involving an essential tyrosyl radical (Y122O·) in …
Development of artificial photosystems based on designed proteins for mechanistic insights into photosynthesis
This review aims to provide an overview of the progress in protein‐based artificial
photosystem design and their potential to uncover the underlying principles governing light …
photosystem design and their potential to uncover the underlying principles governing light …
Proton-Coupled Electron Transfer and a Tyrosine–Histidine Pair in a Photosystem II-Inspired β-Hairpin Maquette: Kinetics on the Picosecond Time Scale
Photosystem II (PSII) and ribonucleotide reductase employ oxidation and reduction of the
tyrosine aromatic ring in radical transport pathways. Tyrosine-based reactions involve either …
tyrosine aromatic ring in radical transport pathways. Tyrosine-based reactions involve either …
Applications of deuterium oxide in human health
WC Bila, RMS Mariano, VR Silva… - … in Environmental and …, 2017 - Taylor & Francis
The main aim goal of this review was to gather information about recent publications related
to deuterium oxide (D2O), and its use as a scientific tool related to human health. Searches …
to deuterium oxide (D2O), and its use as a scientific tool related to human health. Searches …
Redox-driven conformational dynamics in a photosystem-II-inspired β-hairpin maquette determined through spectroscopy and simulation
H Hwang, TG McCaslin, A Hazel… - The Journal of …, 2017 - ACS Publications
Tyrosine-based radical transfer plays an important role in photosynthesis, respiration, and
DNA synthesis. Radical transfer can occur either by electron transfer (ET) or proton coupled …
DNA synthesis. Radical transfer can occur either by electron transfer (ET) or proton coupled …
Redox-linked conformational control of proton-coupled electron transfer: Y122 in the ribonucleotide reductase β2 subunit
AR Offenbacher, LA Burns, CD Sherrill… - The Journal of Physical …, 2013 - ACS Publications
Tyrosyl radicals play essential roles in biological proton-coupled electron transfer (PCET)
reactions. Ribonucleotide reductase (RNR) catalyzes the reduction of ribonucleotides and is …
reactions. Ribonucleotide reductase (RNR) catalyzes the reduction of ribonucleotides and is …
Structure and function of tryptophan–tyrosine dyads in biomimetic β hairpins
Tyrosine–tryptophan (YW) dyads are ubiquitous structural motifs in enzymes and play roles
in proton-coupled electron transfer (PCET) and, possibly, protection from oxidative stress …
in proton-coupled electron transfer (PCET) and, possibly, protection from oxidative stress …