Pathogenesis of cancers derived from thyroid follicular cells
The genomic simplicity of differentiated cancers derived from thyroid follicular cells offers
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …
Anaplastic thyroid carcinoma: an update
Simple Summary Anaplastic thyroid carcinoma (ATC) has a dismal prognostic.
Chemotherapy and radiotherapy are the mainstem options for patients with ATC. In selected …
Chemotherapy and radiotherapy are the mainstem options for patients with ATC. In selected …
2021 American thyroid association guidelines for management of patients with anaplastic thyroid cancer: American thyroid association anaplastic thyroid cancer …
KC Bible, E Kebebew, J Brierley, JP Brito… - Thyroid, 2021 - liebertpub.com
Background: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid
cancer. Since the guidelines for the management of ATC by the American Thyroid …
cancer. Since the guidelines for the management of ATC by the American Thyroid …
Combination of lenvatinib and pembrolizumab is an effective treatment option for anaplastic and poorly differentiated thyroid carcinoma
Background: Anaplastic thyroid carcinoma (ATC) and metastatic poorly differentiated thyroid
carcinomas (PDTCs) are rare aggressive malignancies with poor overall survival (OS) …
carcinomas (PDTCs) are rare aggressive malignancies with poor overall survival (OS) …
Characterizing dedifferentiation of thyroid cancer by integrated analysis
Understanding of dedifferentiation, an indicator of poo prognosis for patients with thyroid
cancer, has been hampered by imprecise and incomplete characterization of its …
cancer, has been hampered by imprecise and incomplete characterization of its …
Anaplastic transformation in thyroid cancer revealed by single-cell transcriptomics
The deadliest anaplastic thyroid cancer (ATC) often transforms from indolent differentiated
thyroid cancer (DTC); however, the complex intratumor transformation process is poorly …
thyroid cancer (DTC); however, the complex intratumor transformation process is poorly …
A whole-genome reference panel of 14,393 individuals for East Asian populations accelerates discovery of rare functional variants
Underrepresentation of non-European (EUR) populations hinders growth of global precision
medicine. Resources such as imputation reference panels that match the study population …
medicine. Resources such as imputation reference panels that match the study population …
Dissecting anaplastic thyroid carcinoma: a comprehensive clinical, histologic, immunophenotypic, and molecular study of 360 cases
Background: Anaplastic thyroid carcinoma (ATC) is nearly always fatal. Large studies on
ATC are exceedingly rare. We aimed to study the clinical, genotypic, and histologic …
ATC are exceedingly rare. We aimed to study the clinical, genotypic, and histologic …
Molecular targets of tyrosine kinase inhibitors in thyroid cancer
P Fallahi, SM Ferrari, MR Galdiero, G Varricchi… - Seminars in cancer …, 2022 - Elsevier
Thyroid cancer (TC) is the eighth most frequently diagnosed cancer worldwide with a rising
incidence in the past 20 years. Surgery is the primary strategy of therapy for patients with …
incidence in the past 20 years. Surgery is the primary strategy of therapy for patients with …
Significance of RAS mutations in thyroid benign nodules and non-medullary thyroid cancer
V Marotta, M Bifulco, M Vitale - Cancers, 2021 - mdpi.com
Simple Summary Only about 4% of thyroid nodules are carcinomas and require surgery.
Fine-needle aspiration cytology is the most accurate tool to distinguish benign from …
Fine-needle aspiration cytology is the most accurate tool to distinguish benign from …