Sickle cell disease
Sickle cell disease (SCD) is a group of inherited disorders caused by mutations in HBB,
which encodes haemoglobin subunit β. The incidence is estimated to be between 300,000 …
which encodes haemoglobin subunit β. The incidence is estimated to be between 300,000 …
Sickle cell disease
Sickle cell disease is caused by an alteration in a single DNA base, but its clinical
manifestations are influenced by other genes and behavioral and environmental factors …
manifestations are influenced by other genes and behavioral and environmental factors …
What can work and how? An overview of evidence-based interventions and delivery strategies to support health and human development from before conception to …
Progress has been made globally in improving the coverage of key maternal, newborn, and
early childhood interventions in low-income and middle-income countries, which has …
early childhood interventions in low-income and middle-income countries, which has …
Sickle cell disease in sub-Saharan Africa
TN Williams - Hematology/Oncology Clinics, 2016 - hemonc.theclinics.com
Sickle hemoglobin (HbS) is a structural variant of normal adult hemoglobin (HbA; a2b2) in
which the normal beta-globin subunit is replaced by a mutant form of the molecule (bS) in …
which the normal beta-globin subunit is replaced by a mutant form of the molecule (bS) in …
[HTML][HTML] Sickle cell disease and infections in high-and low-income countries
G Cannas, S Merazga, E Virot - Mediterranean journal of …, 2019 - ncbi.nlm.nih.gov
Infections, especially pneumococcal septicemia, meningitis, and Salmonella osteomyelitis,
are a major cause of morbidity and mortality in patients with sickle cell disease (SCD). SCD …
are a major cause of morbidity and mortality in patients with sickle cell disease (SCD). SCD …
Angelicin—A Furocoumarin compound with vast biological potential
Angelicin, a member of the furocoumarin group, is related to psoralen which is well known
for its effectiveness in phototherapy. The furocoumarins as a group have been studied since …
for its effectiveness in phototherapy. The furocoumarins as a group have been studied since …
Developing guidelines in low-income and middle-income countries: lessons from Kenya
There are few examples of sustained nationally organised, evidence-informed clinical
guidelines development processes in Sub-Saharan Africa. We describe the evolution of …
guidelines development processes in Sub-Saharan Africa. We describe the evolution of …
Impact of the SARS-CoV-2 infection in individuals with sickle cell disease: an integrative review
LRG Pereira, MVG Da Silva, CMR Germano… - Frontiers in …, 2023 - frontiersin.org
Sickle cell disease is the most common hemoglobinopathy among humans. As the condition
promotes susceptibility to infections, chronic inflammation, and hypercoagulability disorders …
promotes susceptibility to infections, chronic inflammation, and hypercoagulability disorders …
Analysis of causes of hospitalization among children with sickle cell disease in a group of private hospitals in Jeddah, Saudi Arabia
SM Abd El-Ghany, AT Tabbakh, KI Nur… - Journal of Blood …, 2021 - Taylor & Francis
Purpose Sickle cell anemia (SCA) is a chronic hematologic condition that requires frequent
hospitalization representing a significant economic burden on the health services. The aim …
hospitalization representing a significant economic burden on the health services. The aim …
The magic of a methyl group: Biochemistry at the service of medicine
E De Clercq - Biochemical Pharmacology, 2023 - Elsevier
A carbon-carbon linkage is created when a methyl group is implanted on dUMP, thus
resulting in the formation of dTMP by thymidylate synthase. The methyl group is deleted by …
resulting in the formation of dTMP by thymidylate synthase. The methyl group is deleted by …