Mast cell responses to viruses and pathogen products

JS Marshall, L Portales-Cervantes, E Leong - International Journal of …, 2019 - mdpi.com
Mast cells are well accepted as important sentinel cells for host defence against selected
pathogens. Their location at mucosal surfaces and ability to mobilize multiple aspects of …

Mast cells in the skin: defenders of integrity or offenders in inflammation?

M Voss, J Kotrba, E Gaffal… - International Journal of …, 2021 - mdpi.com
Mast cells (MCs) are best-known as key effector cells of immediate-type allergic reactions
that may even culminate in life-threatening anaphylactic shock syndromes. However …

Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity

CQE Lee, B Kerouanton, S Chothani, S Zhang… - Nature …, 2021 - nature.com
Mito-SEPs are small open reading frame-encoded peptides that localize to the mitochondria
to regulate metabolism. Motivated by an intriguing negative association between mito-SEPs …

NKT cells promote Th1 immune bias to dengue virus that governs long-term protective antibody dynamics

Y Choi, WAA Saron, A O'Neill, M Senanayake… - The Journal of Clinical …, 2024 - jci.org
NKT cells are innate-like T cells, recruited to the skin during viral infection, yet their
contributions to long-term immune memory to viruses are unclear. We identified granzyme K …

[HTML][HTML] Mast cells as protectors of health

A Dudeck, M Köberle, O Goldmann, N Meyer… - Journal of Allergy and …, 2019 - Elsevier
Mast cells (MCs), which are well known for their effector functions in TH 2-skewed allergic
and also autoimmune inflammation, have become increasingly acknowledged for their role …

Maternal immunity and antibodies to dengue virus promote infection and Zika virus–induced microcephaly in fetuses

APS Rathore, WAA Saron, T Lim, N Jahan… - Science …, 2019 - science.org
Zika virus (ZIKV), an emergent flaviviral pathogen, has been linked to microcephaly in
neonates. Although the risk is greatest during the first trimester of pregnancy in humans …

Dengue drug discovery: Progress, challenges and outlook

SP Lim - Antiviral research, 2019 - Elsevier
In the context of the only available vaccine (DENGVAXIA) that was marketed in several
countries, but poses higher risks to unexposed individuals, the development of antivirals for …

Mast cells in viral, bacterial, and fungal infection immunity

AM Piliponsky, M Acharya, NJ Shubin - International journal of molecular …, 2019 - mdpi.com
Mast cells are granule-rich immune cells that are distributed throughout the body in areas
where microorganisms typically reside, such as mucosal tissues and the skin, as well as …

Facing the escalating burden of dengue: Challenges and perspectives

GN Malavige, P Sjö, K Singh… - PLOS Global Public …, 2023 - journals.plos.org
Dengue is the most rapidly emerging mosquito-borne infection and, due to climate change
and unplanned urbanization, it is predicted that the global burden of dengue will rise further …

Mast cells promote viral entry of SARS-CoV-2 via formation of chymase/spike protein complex

S Liu, Y Suzuki, E Takemasa, R Watanabe… - European Journal of …, 2022 - Elsevier
The pulmonary pathological findings associated with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) result from the release of multiple proinflammatory cytokines …