Novel microneedle platforms for the treatment of wounds by drug delivery: a review

H An, Z Gu, Z Huang, T Huo, Y Xu, Y Dong… - Colloids and Surfaces B …, 2023 - Elsevier
The management and treatment of wounds are complex and pose a substantial financial
burden to the patient. However, the complex environment of wounds leads to inadequate …

Polymeric Microneedles for Health Care Monitoring: An Emerging Trend

RL Pereira, KB Vinayakumar, S Sillankorva - ACS sensors, 2024 - ACS Publications
Bioanalyte collection by blood draw is a painful process, prone to needle phobia and
injuries. Microneedles can be engineered to penetrate the epidermal skin barrier and collect …

Photothermal microneedle patch loaded with antimicrobial peptide/MnO2 hybrid nanoparticles for chronic wound healing

G Wang, W Wang, Z Chen, T Hu, L Tu, X Wang… - Chemical Engineering …, 2024 - Elsevier
Chronic wound with complex clinical characteristics poses a significant challenge
worldwide. Bioactive and stimulus responsive microneedle patch (MNP) has recently …

Chlorella‐Loaded Antibacterial Microneedles for Microacupuncture Oxygen Therapy of Diabetic Bacterial Infected Wounds

S Gao, Y Rao, X Wang, Q Zhang, Z Zhang… - Advanced …, 2024 - Wiley Online Library
Hypoxia and infection are urgent clinical problems in chronic diabetic wounds. Herein, living
Chlorella‐loaded poly (ionic liquid)‐based microneedles (PILMN‐Chl) are constructed for …

Self‐Sterilizing Microneedle Sensing Patches for Machine Learning‐Enabled Wound pH Visual Monitoring

J Xiao, Z Zhou, G Zhong, T Xu… - Advanced Functional …, 2024 - Wiley Online Library
The skin, as the body's largest organ, is closely linked to an individual's health. Delayed
diagnosis and treatment of skin infections can lead to complications such as non‐healing …

Natural Multifunctional Silk Microcarriers for Noise‐Induced Hearing Loss Therapy

H Zhang, H Chen, L Lu, H Wang, Y Zhao… - Advanced …, 2024 - Wiley Online Library
Noise‐induced hearing loss (NIHL) is a common outcome of excessive reactive oxygen
species in the cochlea, and the targeted delivery of antioxidants to the inner ear is a …

A Multifunctional Rocket‐Like Microneedle System with Thrusters for Self‐Promoted Deep Drug Penetration and Combination Treatment in Melanoma

X Pan, Y Kang, S Zhou, T Zhang… - Advanced Functional …, 2024 - Wiley Online Library
Photodynamic therapy (PDT) proves highly effective in addressing melanoma, and its
synergy with targeted therapy offers a promising avenue in tumor treatment. However, the …

Recent advances in hydrogel microneedle-based biofluid extraction and detection in food and agriculture

S Yao, C Zhang, J Ping, Y Ying - Biosensors and Bioelectronics, 2024 - Elsevier
Microneedle (MN) technology has been extensively studied for its advantages of minimal
invasiveness and user-friendliness. Notably, hydrogel microneedles (HMNs) have garnered …

Modern microelectronics and microfluidics on microneedles

Y Han, J Li, T Chen, B Gao, H Wang - Analyst, 2023 - pubs.rsc.org
Possessing the attractive advantages of moderate invasiveness and high compliance, there
is no doubt that microneedles (MNs) have been a gradually rising star in the field of …

[HTML][HTML] Quercetin-encapsulated GelMa hydrogel microneedle reduces oxidative stress and facilitates wound healing

Y Yi, Z Yang, C Zhou, Y Yang, Y Wu, Q Zhang - Nano TransMed, 2024 - Elsevier
Background Delayed wound healing brings additional physical, mental, and financial
burdens. Microneedles (MNs) are a novel dressing form and can incorporate drug delivery …