Molecular correlates of vaccine-induced protection against typhoid fever
H Zhu, I Chelysheva, DL Cross… - The Journal of …, 2023 - Am Soc Clin Investig
BACKGROUND Typhoid fever is caused by the Gram-negative bacterium Salmonella
enterica serovar Typhi and poses a substantial public health burden worldwide. Vaccines …
enterica serovar Typhi and poses a substantial public health burden worldwide. Vaccines …
Single missense mutations in Vi capsule synthesis genes confer hypervirulence to Salmonella Typhi
Many bacterial pathogens, including the human exclusive pathogen Salmonella Typhi,
express capsular polysaccharides as a crucial virulence factor. Here, through S. Typhi whole …
express capsular polysaccharides as a crucial virulence factor. Here, through S. Typhi whole …
Vi polysaccharide and conjugated vaccines afford similar early, IgM or IgG-independent control of infection but boosting with conjugated Vi vaccines sustains the …
SE Jossi, M Arcuri, A Alshayea, RR Persaud… - Frontiers in …, 2023 - frontiersin.org
Introduction Vaccination with Vi capsular polysaccharide (Vi-PS) or protein-Vi typhoid
conjugate vaccine (TCV) can protect adults against Salmonella Typhi infections. TCVs offer …
conjugate vaccine (TCV) can protect adults against Salmonella Typhi infections. TCVs offer …
Protection Induced by Oral Vaccination with a Recombinant Yersinia pseudotuberculosis Delivering Yersinia pestis LcrV and F1 Antigens in Mice and Rats against …
S Majumder, RM Olson, A Singh, X Wang… - Infection and …, 2022 - Am Soc Microbiol
ABSTRACT A newly attenuated Yersinia pseudotuberculosis strain (designated Yptb1) with
triple mutation Δ asd Δ yopK Δ yopJ and chromosomal insertion of the Y. pestis caf1R-caf1M …
triple mutation Δ asd Δ yopK Δ yopJ and chromosomal insertion of the Y. pestis caf1R-caf1M …
A tool for evaluating heterogeneity in avidity of polyclonal antibodies
Diversity in specificity of polyclonal antibody (pAb) responses is extensively investigated in
vaccine efficacy or immunological evaluations, but the heterogeneity in antibody avidity is …
vaccine efficacy or immunological evaluations, but the heterogeneity in antibody avidity is …
Functional activities of O-polysaccharide and hemolysin coregulated protein 1 specific antibodies isolated from melioidosis patients
A Pumpuang, S Paksanont, MN Burtnick… - Infection and …, 2022 - Am Soc Microbiol
Melioidosis is a fatal tropical disease caused by the environmental Gram-negative
bacterium, Burkholderia pseudomallei. This bacterium is intrinsically resistant to several …
bacterium, Burkholderia pseudomallei. This bacterium is intrinsically resistant to several …
The Whole-Genome Sequencing and Probiotic Profiling of Lactobacillus reuteri Strain TPC32 Isolated from Tibetan Pig
Q Kong, Z Shang, S Nawaz, S Liu, J Li - Nutrients, 2024 - mdpi.com
Gut microbiota are the microbial organisms that play a pivotal role in intestinal health and
during disease conditions. Keeping in view the characteristic functions of gut microbiota, in …
during disease conditions. Keeping in view the characteristic functions of gut microbiota, in …
[PDF][PDF] Vi polysaccharide and conjugated vaccines afford similar early, IgM or IgG-independent control of infection but boosting with conjugated Vi vaccines sustains …
J Andreas, LH Jackson-Jones, K Toellner… - 2023 - pure-oai.bham.ac.uk
Methods and results: Here, we immunized wild-type (WT) mice and mice deficient in IgG or
IgM with Vi-PS or TCVs (Vi conjugated to tetanus toxoid or CRM197) for up to seven months …
IgM with Vi-PS or TCVs (Vi conjugated to tetanus toxoid or CRM197) for up to seven months …
Functional Classes of Naturally Occurring Human Antibodies Developed Against Gram-Negative Bacterial Pathogens
BD Fowler - 2022 - search.proquest.com
Gram-negative bacteria are frequently opportunistic pathogens that cause significant
morbidity and mortality in humans. Escherichia coli and Klebsiella pneumoniae are two …
morbidity and mortality in humans. Escherichia coli and Klebsiella pneumoniae are two …