Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes
HS Kwon, SH Koh - Translational neurodegeneration, 2020 - Springer
Neuroinflammation is associated with neurodegenerative diseases, such as Alzheimer's
disease, Parkinson's disease, and amyotrophic lateral sclerosis. Microglia and astrocytes …
disease, Parkinson's disease, and amyotrophic lateral sclerosis. Microglia and astrocytes …
The impact of systemic inflammation on Alzheimer's disease pathology
J Xie, L Van Hoecke, RE Vandenbroucke - Frontiers in immunology, 2022 - frontiersin.org
Alzheimer's disease (AD) is a devastating age-related neurodegenerative disorder with an
alarming increasing prevalence. Except for the recently FDA-approved Aducanumab of …
alarming increasing prevalence. Except for the recently FDA-approved Aducanumab of …
Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
L Ferrucci, E Fabbri - Nature Reviews Cardiology, 2018 - nature.com
Most older individuals develop inflammageing, a condition characterized by elevated levels
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …
Lipid metabolism and Alzheimer's disease: clinical evidence, mechanistic link and therapeutic promise
F Yin - The FEBS journal, 2023 - Wiley Online Library
Alzheimer's disease (AD) is an age‐associated neurodegenerative disorder with
multifactorial etiology, intersecting genetic and environmental risk factors, and a lack of …
multifactorial etiology, intersecting genetic and environmental risk factors, and a lack of …
Dementia prevention, intervention, and care
Executive summary Acting now on dementia prevention, intervention, and care will vastly
improve living and dying for individuals with dementia and their families, and in doing so …
improve living and dying for individuals with dementia and their families, and in doing so …
Cellular senescence and Alzheimer disease: the egg and the chicken scenario
S Saez-Atienzar, E Masliah - Nature Reviews Neuroscience, 2020 - nature.com
Globally, 50 million people live with dementia, with Alzheimer disease (AD) being
responsible for two-thirds of the total cases. As ageing is the main risk factor for dementia …
responsible for two-thirds of the total cases. As ageing is the main risk factor for dementia …
Defeating Alzheimer's disease and other dementias: a priority for European science and society
Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …
A path toward precision medicine for neuroinflammatory mechanisms in Alzheimer's disease
Neuroinflammation commences decades before Alzheimer's disease (AD) clinical onset and
represents one of the earliest pathomechanistic alterations throughout the AD continuum …
represents one of the earliest pathomechanistic alterations throughout the AD continuum …
Neuroinflammation in Alzheimer's disease
Increasing evidence suggests that Alzheimer's disease pathogenesis is not restricted to the
neuronal compartment, but includes strong interactions with immunological mechanisms in …
neuronal compartment, but includes strong interactions with immunological mechanisms in …
Immune attack: the role of inflammation in Alzheimer disease
The past two decades of research into the pathogenesis of Alzheimer disease (AD) have
been driven largely by the amyloid hypothesis; the neuroinflammation that is associated with …
been driven largely by the amyloid hypothesis; the neuroinflammation that is associated with …