The invention relates to immunotherapeutic compounds and to methods for stimulating an
immune response in a subject individual at risk for developing cancer, diagnosed with a …

(57) ABSTRACT A composition comprising (a) Neisseria meningitidis sero group B outer
membrane vesicles (OMVs), and (b) an immu nogenic component selected from …

EP O449958 3, 1995 EP 1208214 11, 2006 WO WO 9006696 6, 1990 WO WO962. 9412 9,
1996 WO WO98O2547 1, 1998 WO WO9856, 901 12/1998 WO WO992. 4578 5, 1999 WO …

US9034345B2 - GNA1870-based vesicle vaccines for broad spectrum protection against
diseases caused by Neisseria meningitidis - Google Patents US9034345B2 - GNA1870-based …

A composition is prepared from a mixture of different vesicles, such as outer membrane
vesicles (OMVs) and vaccines are based thereon. Another composition comprises in a …

US6936261B2 - Vaccines for broad spectrum protection against diseases caused by Neisseria
meningitidis - Google Patents US6936261B2 - Vaccines for broad spectrum protection against …

A mucosal vaccine for Neisseria based on native outer membrane vesicles (NOMV)
prepared from genetically engineered vaccine strain and unexposed to detergents is …

The present invention is directed to novel compounds that function as immunological
adjuvants when co-administered with antigens Such as vaccines for bacterial and viral …

Existing methods of meningococcal OMV preparation involve the use of detergent during
disruption of the bacte rial membrane. According to the invention, membrane dis ruption is …

The present invention is directed to novel compounds that function as immunological
adjuvants when co-administered with antigens Such as vaccines for bacterial and viral …